[Comment: For dates of non-regulatory government publications, publications of recognized organizations and associations, federal rules, and federal statutory provisions referenced in this rule, see rule 3745-300-15 of the Administrative Code titled "Incorporation by reference - voluntary action program."]
Equation 1 - cumulative cancer risk ratio for affected media
[(chema/SCCSa) + (chemb/SCCSb) + ...] = cumulative cancer risk ratio
Equation 2 - cumulative noncancer risk ratio for affected media
[(chema/SCNSa) + (chemb/SCNSb) + ...] = cumulative noncancer risk ratio
Non-cancer risk ratios for non-carcinogenic COCs which do not exhibit the same toxic endpoint may be excluded from the calculation of the cumulative non-cancer risk ratio described above if a written justification for such exclusion is submitted. The consideration of all major toxic endpoints and mechanisms of action shall include, at a minimum, those identified with the critical effect upon which the reference dose or reference concentration for each non-carcinogenic COC is based. The source for each reference dose and reference concentration for each non-carcinogenic chemical for which generic direct-contact soil standards are derived, are cited in Ohio EPA's "Support Document for the Development of Generic Numerical Standards and Risk Assessment Procedures." It may be necessary to calculate more than one cumulative non-cancer risk ratio for a property that results from the segregation of non-carcinogenic COCs based on toxic endpoints or mechanisms of action.
Replaces: 3745-300-08, 3745-300-08 appendix
Ohio Admin. Code 3745-300-08
Five Year Review (FYR) Dates: 10/17/2024
Promulgated Under: 119.03
Statutory Authority: 3746.04
Rule Amplifies: 3746.04
Prior Effective Dates: 12/16/1996, 10/21/2002, 03/01/2009, 08/01/2014, 05/26/2016