N.J. Admin. Code § Tit. 7, ch. 26D, app 11
TOXICITY FACTORS USED IN THE DEVELOPMENT OF THE REMEDIATION STANDARDS
Table 1-Soil Ingestion-Dermal Toxicity Factors
| Contaminant | CAS No. | Soil Ingestion-dermal Recommendation | Soil Ingestion-dermal Toxicity Factor(s) |
| Acenaphthene | 83-32-9 | IRIS RfD with a dermal absorption fraction (ABS) | IRIS RfD (1994) 0.06 mg/kg-day ABS 0.13 |
| Acetone | 67-64-1 | IRIS RfD | IRIS RfD (2003) 0.9 mg/kg-day |
| Acetophenone | 98-86-2 | IRIS RfD | IRIS RfD (1989) 0.1 mg/kg-day |
| Aldrin | 309-00-2 | IRIS Slope Factor (SF) RfD | IRIS SF (1993) 17 (mg/kg-day)-1 IRIS RfD (1988) 0.00003 mg/kg-day |
| Aluminum | 7429-90-5 | PPRTV RfD | PPRTV RfD (2006) 1.0 mg/kg-day |
| Anthracene | 120-12-7 | IRIS RfD with a dermal absorption fraction (ABS) | IRIS RfD (1993) 0.3 mg/kg-day ABS 0.13 |
| Antimony | 7440-36-0 | IRIS RfD with a gastrointestinal absorption fraction (GIABS) | IRIS RfD (1991) 0.0004 mg/kg-day GIABS 0.15 |
| Arsenic | 7440-38-2 | IRIS Slope Factor (SF) with a dermal absorption fraction (ABS) IRIS RfD with a dermal absorption fraction (ABS) | IRIS SF (1998) 1.5 (mg/kg-day)-1 IRIS RfD (1993) 0.0003 mg/kg-day ABS 0.03 |
| Atrazine | 1912-24-9 | IRIS RfD with a dermal absorption fraction (ABS) and a Group C carcinogen factor | IRIS RfD (1993) 0.035 mg/kg-day ABS 0.1 Group C carcinogen factor 10 |
| Barium | 7440-39-3 | IRIS RfD with a gastrointestinal absorption fraction (GIABS) | IRIS RfD (2005) 0.2 mg/kg-day GIABS 0.07 |
| Benzaldehyde | 100-52-7 | PPRTV Slope Factor (SF) IRIS RfD | PPRTV SF (2015) 4E-03 (mg/kg-day)-1 IRIS RfD (1988) 0.1 mg/kg-day |
| Benzene | 71-43-2 | NJDWQI Slope Factor (SF) IRIS RfD1 | NJDWQI SF (1994) 0.23 (mg/kg-day)-1 IRIS RfD (2003) 0.004 mg/kg-day |
| Benzo(a)anthracene | 56-55-3 | IRIS Slope Factor (SF) (benzo(a)pyrene -adjusted for benzo(a) pyrene) with a dermal absorption fraction (ABS) | IRIS SF (2017) 1.0E-01(mg/kg-day)-1 (adjusted for benzo (a)anthracene) ABS 0.13 |
| Benzo(a)pyrene | 50-32-8 | IRIS Slope Factor (SF) with a dermal absorption fraction (ABS) | IRIS SF (2017) 1.0E +00 (mg/kg-day)-1 |
| IRIS RfD with a dermal absorption fraction (ABS) | IRIS RfD (2017) 3.0E-04 mg/kg-day ABS 0.13 | ||
| IRIS Slope Factor (SF) (benzo(a)pyrene - | IRIS SF (2017) 1.0E-01 (mg/kg- | ||
| Benzo(b)fluoranthene | 205-99-2 | adjusted for benzo(b) fluoranthene) with a dermal absorption fraction (ABS) | day)-1 (adjusted for benzo (b)fluoranthene) ABS 0.13 |
| Benzo(k)fluoranthene | 207-08-9 | IRIS Slope Factor (SF) (benzo(a)pyrene -adjusted for benzo(k) fluoranthene) with a dermal absorption fraction (ABS) | IRIS SF (2017) 1.0E-02(mg/kg-day)-1 (adjusted for benzo(k) fluoranthene) ABS 0.13 |
| Beryllium | 7440-41-7 | IRIS RfD with a gastrointestinal absorption fraction (GIABS) | IRIS RfD (1998) 0.002 mg/kg-day GIABS 0.007 IRIS SF (2013) |
| 1,1'-Biphenyl | 92-52-4 | IRIS Slope Factor (SF) IRIS RfD | 0.008 (mg/kg-day)- 1 IRIS RfD (2013) 0.5 mg/kg-day |
| Bis(2-chloroethoxy) methane | 111-91-1 | PPRTV RfD with a dermal absorption fraction (ABS) | PPRTV RfD (2006) 0.003 mg/kg-day ABS 0.1 |
| Bis(2-chloroethyl) ether | 111-44-4 | IRIS Slope Factor (SF) | IRIS SF (1994) 1.1 (mg/kg-day)-1 |
| Bis(2-ethylhexyl) phthalate | 117-81-7 | IRIS Slope Factor (SF) with a dermal absorption fraction (ABS) IRIS RfD with a dermal absorption fraction (ABS) | IRIS SF (1993) 0.014 (mg/kg-day)-1 IRIS RfD (2013) 0.02 mg/kg-day ABS 0.1 |
| Bromodichloromethane | 75-27-4 | IRIS Slope Factor (SF) IRIS RfD | IRIS SF (1993) 0.062 (mg/kg-day)-1 IRIS RfD (1991) 0.02 mg/kg-day IRIS SF (1991) |
| Bromoform | 75-25-2 | IRIS Slope Factor (SF) IRIS RfD | 0.0079 (mg/kg-day)-1 IRIS RfD (1991) 0.02 mg/kg-day |
| Bromomethane | 74-83-9 | IRIS RfD | IRIS RfD (1991) 0.0014 mg/kg-day |
| 2-Butanone | 78-93-3 | IRIS RfD2 | IRIS RfD (2003) 0.6 mg/kg-day |
| Butylbenzylphthalate | 85-68-7 | PPRTV Slope Factor (SF) with a dermal absorption fraction (ABS) IRIS RfD with a dermal absorption fraction (ABS) and a Group C carcinogen factor | PPRTV SF (2002) 0.0019 (mg/kg-day)-1 IRIS RfD (2013) 0.2 mg/kg-day ABS 0.1 Group C carcinogen factor 10 |
| Cadmium | 7440-43-9 | IRIS RfD with a dermal absorption fraction (ABS) and gastrointestinal absorption fraction (GIABS) | IRIS RfD (1994) 0.001 mg/kg-day ABS 0.001 GIABS 0.025 |
| Caprolactam | 105-60-2 | IRIS RfD with a dermal absorption fraction (ABS) | IRIS RfD (1988) 0.5 mg/kg-day ABS 0.1 |
| Carbon disulfide | 75-15-0 | No ingestion-based toxicity factors are available | None |
| Carbon tetrachloride | 56-23-5 | NJDWQI Slope Factor (SF) IRIS RfD | NJDWQI SF (1994) 0.091 (mg/kg-day)-1 IRIS RfD (2011) 0.004 mg/kg-day |
| Chlordane (alpha plus gamma mix | ture) 57-74-9 | NJDWQI Slope Factor (SF) with a dermal absorption fraction (ABS) IRIS RfD with a dermal absorption fraction (ABS) PPRTV Slope Factor (SF) with a dermal absorption | NJDWQI SF (2001) 2.3 (mg/kg-day)-1 IRIS RfD (1998) 0.0005 mg/kg-day ABS 0.04 PPRTV SF (2008) 0.2 (mg/kg-day)-1 |
| 4-Chloroaniline | 106-47-8 | fraction (ABS) IRIS RfD with a dermal absorption fraction (ABS) | IRIS RfD (1995) 0.004 mg/kg-day ABS 0.1 |
| Chlorobenzene | 108-90-7 | NJDWQI RfD | NJDWQI RfD (1994) 0.0065 mg/kg-day |
| Chloroethane | 75-00-3 | No ingestion-based toxicity factors are available | None |
| Chloroform | 67-66-3 | IRIS RfD3 | IRIS RfD (2001) 0.01 mg/kg-day |
| Chloromethane | 74-87-3 | No ingestion-based toxicity factors are available | None |
| 2-Chloronaphthalene | 91-58-7 | IRIS RfD with a dermal absorption fraction (ABS) | IRIS RfD (1990) 0.08 mg/kg-day ABS 0.13 |
| 2-Chlorophenol | 95-57-8 | IRIS RfD | IRIS RfD (1993) 0.005 mg/kg-day |
| Chrysene | 218-01-9 | IRIS Slope Factor (SF) (benzo(a)pyrene-adjusted for chrysene) with a dermal absorption fraction (ABS) | IRIS SF (2017) 1.0E-03 (mg/kg-day)-1 (adjusted for chrysene) ABS 0.13 |
| Cobalt | 7440-48-4 | PPRTV RfD | PPRTV RfD (2008) 0.0003 mg/kg-day |
| Copper | 7440-50-8 | HEAST RfD | HEAST RfD (1997) 0.04 mg/kg-day |
| Cyanide | 57-12-5 | IRIS RfD | IRIS RfD (2010) 0.0006 mg/kg-day |
| Cyclohexane | 110-82-7 | No ingestion-based toxicity factors are available | None |
| 4,4'-DDD | 72-54-8 | IRIS Slope Factor (SF) with a dermal absorption fraction (ABS) | IRIS SF (1988) 0.24 (mg/kg-day)-1 ABS 0.1 |
| 4,4'-DDE | 72-55-9 | IRIS SF | |
| 4,4'-DDT | 50-29-3 | IRIS Slope Factor (SF) with a dermal absorption fraction (ABS) IRIS RfD with a dermal absorption fraction (ABS) | IRIS SF (1991) 0.34 (mg/kg-day)-1 IRIS RfD (1996) 0.0005 mg/kg-day ABS 0.03 |
| Dibenz(a,h)anthracene | 53-70-3 | IRIS Slope Factor (SF) (benzo(a)pyrene-adjusted for dibenz(a,h) anthracene) with a dermal absorption fraction (ABS) | IRIS SF (2017) 1.0E+00 (mg/kg-day)-1 (adjusted for dibenz(a,h) anthracene) ABS 0.13 |
| Dibromochloromethane | 124-48-1 | IRIS Slope Factor (SF) IRIS RfD and a Group C carcinogen factor | IRIS SF (1992) 0.084 (mg/kg-day)-1 IRIS RfD (1991) 0.02 mg/kg-day Group C carcinogen factor 10 PPRTV SF (2006) |
| 1,2-Dibromo-3-chloropropane | 96-12-8 | PPRTV Slope Factor (SF) PPRTV RfD | 0.8 (mg/kg-day)-1 PPRTV RfD (2006) 0.0002 mg/kg-day IRIS SF (2004) |
| 1,2-Dibromoethane | 106-93-4 | IRIS Slope Factor (SF) IRIS RfD | 2.0 (mg/kg-day)-1 IRIS RfD (2004) 0.009 mg/kg-day NJDWQI RfD |
| 1,2-Dichlorobenzene | 95-50-1 | NJDWQI RfD | (1994) 0.086 mg/kg-day NJDWQI RfD |
| 1,3-Dichlorobenzene | 541-73-1 | NJDWQI RfD | (1994) 0.086 mg/kg-day NJDWQI RfD (1994) |
| NJDWQI RfD with a | 0.01 mg/kg-day | ||
| 1,4-Dichlorobenzene | 106-46-7 | Group C carcinogen | (RfD includes |
| factor4 | Group C Carcinogen factor adjustment of 10) | ||
| 3,3'-Dichlorobenzidine | 91-94-1 | IRIS Slope Factor (SF) with a dermal absorption fraction (ABS) | IRIS SF (1993) 0.45 (mg/kg-day)-1 ABS 0.1 |
| Dichlorodifluoromethane | 75-71-8 | IRIS RfD | IRIS RfD (1995) 0.2 mg/kg-day |
| CalEPA SF (1992) | |||
| 1,1-Dichloroethane | 75-34-3 | CalEPA Slope Factor (SF) PPRTV RfD5 | 0.0057 (mg/kg- day)-1 PPRTV RfD (2006) 0.2 mg/kg-day |
| 1,2-Dichloroethane | 107-06-2 | NJDWQI Slope Factor (SF)6 | NJDWQI SF (1994) 0.12 (mg/kg-day)-1 |
| NJDWQI RfD (1994) | |||
| NJDWQI RfD with a | 0.00014 mg/kg-day | ||
| 1,1-Dichloroethene | 75-35-4 | Group C carcinogen | (RfD includes |
| factor | Group C Carcinogen factor adjustment of 10) | ||
| NJDWQI RfD | |||
| cis-1,2-Dichloroethene | 156-59-2 | NJDWQI RfD | (1994) 0.01 mg/kg-day NJDWQI RfD |
| trans-1,2-Dichloroethene | 156-60-5 | NJDWQI RfD | (1994) 0.017 mg/kg-day |
| 2,4-Dichlorophenol | 120-83-2 | IRIS RfD with a dermal absorption fraction (ABS) | IRIS RfD (1988) 0.003 mg/kg-day ABS 0.1 PPRTV SF (2016) |
| 1,2-Dichloropropane | 78-87-5 | PPRTV Slope Factor (SF) PPRTV RfD | 0.037 (mg/kg-day)-1 PPRTV RfD (2016) 0.04 mg/kg-day IRIS SF (2000) |
| 1,3-Dichloropropene (cis and trans) | 542-75-6 | IRIS Slope Factor (SF) IRIS RfD | 0.1 (mg/kg-day)-1 IRIS RfD (2000) 0.03 mg/kg-day |
| Dieldrin | 60-57-1 | IRIS Slope Factor (SF) with a dermal absorption fraction (ABS) IRIS RfD with a dermal absorption fraction (ABS) | IRIS SF (1993) 16 (mg/kg-day)-1 IRIS RfD (1990) 0.00005 mg/kg-day ABS 0.1 |
| Diethylphthalate | 84-66-2 | IRIS RfD with a dermal absorption fraction (ABS) | IRIS RfD (1993) 0.8 mg/kg-day ABS 0.1 |
| 2,4-Dimethylphenol | 105-67-9 | IRIS RfD with a dermal absorption fraction (ABS) | IRIS RfD (1990) 0.02 mg/kg-day ABS 0.1 |
| Di-n-butylphthalate | 84-74-2 | IRIS RfD with a dermal absorption fraction (ABS) | IRIS RfD (1990) 0.1 mg/kg-day ABS 0.1 |
| 2,4-Dinitrophenol | 51-28-5 | IRIS RfD with a dermal absorption fraction (ABS) | IRIS RfD (1991) 0.002 mg/kg-day ABS 0.1 |
| 2,4-Dinitrotoluene /2,6-Dinitrotoluene (mixture) | 25321-146 | IRIS Slope Factor (SF) with a dermal absorption fraction (ABS) | IRIS SF (1990) 0.68 (mg/kg-day)-1 ABS 0.1 |
| Di-n-octylphthalate | 117-84-0 | PPRTV RfD with a dermal absorption fraction (ABS) | PPRTV RfD (2012) 0.01 mg/kg-day ABS 0.1 IRIS SF (2013) |
| 1,4-Dioxane | 123-91-1 | IRIS Slope Factor (SF) IRIS RfD | 0.1 (mg/kg-day)-1 IRIS RfD (2010) 0.03 mg/kg-day |
| Endosulfan I and Endosulfan II | 115-29-7 | IRIS RfD | |
| Endrin | 72-20-8 | IRIS RfD with a dermal absorption fraction (ABS) | IRIS RfD (1991) 0.0003 mg/kg-day ABS 0.1 |
| Ethylbenzene | 100-41-4 | IRIS RfD7 | IRIS RfD (1991) 0.1 mg/kg-day |
| Extractable Petroleum Hydrocarbons (EPH) (Category 1) | various | N.J.A.C. 7:26D-Appendix 2, Equation 5 | See Table 1a-EPH Toxicity (below) |
| Extractable Petroleum Hydrocarbons (EPH) (Category 2) | various | N.J.A.C. 7:26D-Appendix 2, Equation 5 | See Table 1a-EPH Toxicity (below) |
| Fluoranthene | 206-44-0 | IRIS RfD with a dermal absorption fraction (ABS) | IRIS RfD (1993) 0.04 mg/kg-day ABS 0.13 |
| Fluorene | 86-73-7 | IRIS RfD with a dermal absorption fraction (ABS) | IRIS RfD (1990) 0.04 mg/kg-day ABS 0.13 |
| alpha-HCH (alpha-BHC) | 319-84-6 | IRIS Slope Factor (SF) with a dermal absorption fraction (ABS) ATSDR RfD with a dermal absorption fraction (ABS) | IRIS SF (1993) 6.3 (mg/kg-day)-1 ATSDR RfD (2013) 0.008 mg/kg-day ABS 0.1 |
| beta-HCH (beta-BHC) | 319-85-7 | IRIS Slope Factor (SF) with a dermal absorption fraction (ABS) and Group C carcinogen factor | IRIS SF (1993) 1.8 (mg/kg-day)-1 ABS 0.1 Group C carcinogen factor 10 |
| Heptachlor | 76-44-8 | IRIS Slope Factor (SF) IRIS RfD | |
| Heptachlor epoxide | 1024-57-3 | IRIS Slope Factor (SF) IRIS RfD | |
| Hexachlorobenzene | 118-74-1 | IRIS Slope Factor (SF) IRIS RfD | |
| IRIS Slope Factor (SF) | IRIS SF (1991) 0.078 (mg/kg-day)-1 | ||
| Hexachloro-1,3-butadiene | 87-68-3 | PPRTV RfD with a Group C carcinogen factor | PPRTV RfD (2007) 0.001 mg/kg-day Group C carcinogen factor 10 |
| Hexachlorocyclopentadiene | 77-47-4 | IRIS RfD | |
| IRIS Slope Factor (SF) | IRIS SF (2011) 0.04 (mg/kg-day)- | ||
| Hexachloroethane | 67-72-1 | IRIS RfD | |
| n-Hexane | 110-54-3 | No ingestion-based toxicity factors are available17 | None |
| 2-Hexanone | 591-78-6 | IRIS RfD IRIS Slope Factor (SF) (benzo(a)pyrene-- | IRIS RfD (2009) 0.005 mg/kg-day IRIS SF (2017) 1.0E-01(mg/kg- |
| Indeno(1,2,3-cd) pyrene | 193-39-5 | adjusted for indeno (1,2,3-cd)pyrene) with a dermal absorption | day)-1 (adjusted for indeno(1,2,3-cd) pyrene) |
| fraction (ABS). IRIS Slope Factor (SF) | ABS 0.13 | ||
| Isophorone | 78-59-1 | with a dermal absorption fraction (ABS) | IRIS SF (1992) 0.00095 (mg/kg- |
| IRIS RfD with a dermal absorption fraction (ABS) and a Group C carcinogen factor | day)-1 IRIS RfD (2003) 0.2 mg/kg-day ABS 0.1 Group C carcinogen factor 10 | ||
| Isopropylbenzene | 98-82-8 | IRIS RfD USEPA IEUBK model for | IRIS RfD (1997) 0.1 mg/kg-day IEUBK (1994) |
| Lead | 7439-92-1 | children USEPA ALM for adults | Children ALM (1996) Adults |
| CalEPA Slope Factor (SF) with a | 1.1 (mg/kg-day)-1 | ||
| Lindane (gamma-HCH) (gamma-BHC) | 58-89-9 | dermal absorption fraction (ABS) | IRIS RfD (1988) 0.0003 mg/kg-day |
| IRIS RfD with a dermal absorption fraction (ABS) | ABS 0.04 EPA RSL RfD | ||
| Manganese | 7439-96-5 | EPA RSL RfD | (2018) 0.024 mg/kg-day |
| Mercury | 7439-97-6 | IRIS RfD with a gastrointestinal absorption fraction (GIABS) | IRIS RfD (1995) 0.0003 mg/kg-day GIABS 0.07 |
| Methoxychlor | 72-43-5 | IRIS RfD with a dermal absorption fraction (ABS) | IRIS RfD (1991) 0.005 mg/kg-day ABS 0.1 |
| Methyl acetate | 79-20-9 | HEAST RfD | HEAST RfD (1997) 1.0 mg/kg-day |
| NJDWQI Slope Factor | NJDWQI SF (1994) 0.014 (mg/kg-day)- | ||
| Methylene chloride | 75-09-2 | (SF) IRIS RfD | 1 IRIS RfD (2011) 0.006 mg/kg-day |
| 2-Methylnaphthalene | 91-57-6 | IRIS RfD with a dermal absorption fraction (ABS) | IRIS RfD (2003) 0.004 mg/kg-day ABS 0.13 |
| 4-Methyl-2-pentanone | 108-10-1 | No ingestion-based toxicity factors are available | None |
| 2-Methylphenol | 95-48-7 | IRIS RfD with a dermal absorption fraction (ABS) and a Group C carcinogen factor | IRIS RfD (2008) 0.05 mg/kg-day ABS 0.1 Group C carcinogen factor 10 |
| 4-Methylphenol | 106-44-5 | ATSDR RfD with a dermal absorption fraction (ABS) and a Group C carcinogen factor | ATSDR RfD (2013) 0.1 mg/kg-day ABS 0.1 Group C carcinogen factor 10 |
| NJDWQI RfD (1994) | |||
| NJDWQI RfD with a | 0.01 mg/kg-day | ||
| Methyl tert-butyl ether (MTBE) | 1634-04-4 | Group C carcinogen factor8 | (RfD includes Group C Carcinogen factor adjustment of 10) |
| Naphthalene | 91-20-3 | NJDWQI RfD with a dermal absorption fraction (ABS) and a Group C carcinogen factor | NJDWQI RfD (1994) 0.041 mg/kg-day ABS 0.13 (RfD includes Group C Carcinogen factor adjustment of 10) |
| Nickel | 7440-02-0 | IRIS RfD with a gastrointestinal absorption fraction (GIABS) | IRIS RfD (1996) 0.02 mg/kg-day GIABS 0.04 IRIS SF (2009) |
| 4-Nitroaniline | 100-01-6 | IRIS Slope Factor (SF) with a dermal absorption fraction (ABS) PPRTV RfD with a dermal absorption fraction (ABS) | 0.02 (mg/kg-day)-1 PPRTV RfD (2009) 0.004 mg/kg-day 0.0049 (mg/kg-day)-1 ABS 0.1 |
| Nitrobenzene | 98-95-3 | IRIS RfD | IRIS RfD (2009) 0.002 mg/kg-day |
| N-Nitroso-di-n-propylamine | 621-64-7 | IRIS Slope Factor (SF) with a dermal absorption fraction (ABS) | IRIS SF (1993) 7.0 (mg/kg-day)-1 ABS 0.1 |
| N-Nitrosodiphenylamine | 86-30-6 | IRIS Slope Factor (SF) with a dermal absorption fraction (ABS) | IRIS SF (1993) 0.0049 (mg/kg-day)-1 ABS 0.1 |
| 2,2'-Oxybis(1-choloropropane) | 108-60-1 | IRIS RfD | IRIS RfD (1991) 0.04 mg/kg-day |
| Pentachlorophenol | 87-86-5 | IRIS Slope Factor (SF) with a dermal absorption fraction (ABS) IRIS RfD with a dermal absorption fraction (ABS) | IRIS SF (2010) 0.4 (mg/kg-day)-1 IRIS RfD (2010) 0.005 mg/kg-day ABS 0.25 |
| Phenol | 108-95-2 | IRIS RfD with a dermal absorption fraction (ABS) | IRIS RfD (2002) 0.3 mg/kg-day ABS 0.1 |
| Polychlorinated biphenyls (PCBs) | 1336-36-3 | NJDWQI Slope Factor (SF) with a dermal absorption fraction (ABS) | NJDWQI SF (1994) 2 (mg/kg-day)-1 ABS 0.14 |
| Pyrene | 129-00-0 | IRIS RfD with a dermal absorption fraction (ABS) | IRIS RfD (1993) 0.03 mg/kg-day ABS 0.13 |
| Selenium | 7782-49-2 | IRIS RfD | IRIS RfD (1991) 0.005 mg/kg-day |
| Silver | 7440-22-4 | IRIS RfD with a gastrointestinal absorption fraction (GIABS) | IRIS RfD (1996) 0.005 mg/kg-day GIABS 0.04 |
| Styrene | 100-42-5 | IRIS RfD | IRIS RfD (1990) 0.2 mg/kg-day |
| NJDEP RfD (1997) 0.018 mg/kg-day | |||
| Tertiary butyl alcohol (TBA) | 75-65-0 | NJDEP RfD with a Group C carcinogen factor | (RfD includes Group C Carcinogen factor adjustment of 10) |
| 1,2,4,5-Tetrachlorobenzene | 95-94-3 | IRIS RfD | |
| 2,3,7,8-Tetrachlorodibenzo-p-dioxin | 1746-01-6 | IRIS RfD with a dermal absorption fraction (ABS) | IRIS RfD (2012) 7E-10 mg/kg-day ABS 0.03 IRIS SF (2010) |
| 1,1,2,2-Tetrachloroethane | 79-34-5 | IRIS Slope Factor (SF) IRIS RfD9 | 0.2 (mg/kg-day)-1 IRIS RfD (2010) 0.02 mg/kg-day IRIS SF (2012) |
| Tetrachloroethene (PCE) | 127-18-4 | IRIS Slope Factor (SF) IRIS RfD10 | 0.0021 (mg/kg-day)-1 IRIS RfD (2012) 0.006 mg/kg-day |
| 2,3,4,6-Tetrachlorophenol | 58-90-2 | IRIS RfD with a dermal absorption fraction (ABS) | IRIS RfD (1992) 0.03 mg/kg-day ABS 0.1 |
| Toluene | 108-88-3 | IRIS RfD | IRIS RfD (2005) 0.08 mg/kg-day |
| Toxaphene | 8001-35-2 | IRIS Slope Factor (SF) with a dermal absorption fraction (ABS) | IRIS SF (1991) 1.1 (mg/kg-day)-1 ABS 0.1 IRIS RfD (1996) |
| 1,2,4-Trichlorobenzene | 120-82-1 | IRIS RfD11 | 0.01 mg/kg-day |
| 1,1,1-Trichloroethane | 71-55-6 | IRIS RfD12 | IRIS RfD (2007) 2 mg/kg-day IRIS SF (2011) |
| Trichloroethene (TCE) | 79-01-6 | IRIS Slope Factor (SF)14 IRIS RfD | 0.046 (mg/kg-day)-1 IRIS RfD (2011) 0.0005 mg/kg-day |
| Trichlorofluoromethane | 75-69-4 | IRIS RfD | IRIS RfD (1992) 0.3 mg/kg-day |
| 2,4,5-Trichlorophenol | 95-95-4 | IRIS RfD with a dermal absorption fraction (ABS) | IRIS RfD (1988) 0.1 mg/kg-day ABS 0.1 |
| 2,4,6-Trichlorophenol | 88-06-2 | IRIS Slope Factor (SF) with a dermal absorption fraction (ABS) PPRTV RfD with a dermal absorption fraction (ABS) | IRIS SF (1994) 0.011 (mg/kg-day)-1 PPRTV RfD (2007) 0.001 mg/kg-day ABS 0.1 |
| 1,1,2-Trichloro-1,2,2-trifluoroethane | 76-13-1 | No ingestion-based toxicity factors are available15 | None |
| 1,2,4-Trimethylbenzene | 95-63-6 | IRIS RfD | IRIS RfD (2016) 0.01 mg/kg-day |
| Vanadium | 7440-62-2 | EPA RSL RfD with a gastrointestinal absorption fraction | EPA RSL RfD (2018) 0.005 mg/kg-day GIABS 0.026 |
| Vinyl Chloride | 75-01-4 | IRIS Slope Factor (SF) | IRIS SF (2000) 0.72 (mg/kg-day)- |
| IRIS RfD16 | 1 IRIS RfD (2000) 0.003 mg/kg-day NJDWQI RfD | ||
| Xylenes | 1330-20-7 | NJDWQI RfD | (1994) 0.15 mg/kg-day |
| Zinc | 7440-66-6 | IRIS RfD | IRIS RfD (2005) 0.3 mg/kg-day |
Table 1a--EPH Toxicity
Applies to both:
EPH - Category 1 (Number 2 Heating Oil/Diesel Fuel)
EPH - Category 2 (Heavier petroleum products)
Note: EPH excludes lighter petroleum products including gasoline and mineral spirits
| Effective Carbon Range Aliphatics | Surrogate | Toxicity Factor | Toxicity Factor Reference Source |
| 9 - 12 | PHC Mixture | RfD 0.10 mg/kg-day ABS 0.1 | Canada 2000 and MADEP 2003 |
| 12 - 16 | PHC Mixture | RfD 0.10 mg/kg-day ABS 0.1 | Canada 2000 and MADEP 2003 |
| 16 - 21 | White Mineral Oil | RfD 2.0 mg/kg-day ABS 0.1 | TPHCWG 1997 and MADEP 2003 |
| 21 - 40 | White Mineral Oil | RfD 2.0 mg/kg-day ABS 0.1 | TPHCWG 1997 and MADEP 2003 |
| Effective Carbon Range Aromatics | Surrogate | Toxicity Factor | Toxicity Factor Reference Source |
| 10 - 12 | Naphthalene | RfD 0.041 mg/kg-day ABS 0.13 | NJDWQI (1994) |
| 12 - 16 | Acenaphthene | RfD 0.06 mg/kg-day ABS 0.13 | IRIS (1994) |
| 16 - 21 | Fluorene | RfD 0.04 mg/kg-day ABS 0.13 | IRIS (1990) |
| 21 - 36 | Fluoranthene | RfD 0.04 mg/kg-day | IRIS (1993) |
1 Both the NJDWQI slope factor and IRIS RfD for benzene are based on a route to route conversion of an inhalation study, which was determined to be acceptable by the USEPA as substantiated by additional evaluation including physiologically-based pharmacokinetic modeling.
2 Although a NJDWQI RfD for 2-butanone exists, it is based on an inhalation route-to-route conversion. The Department's Site Remediation and Waste Management Program policy does not allow, except where warranted, for the development of soil remediation standards based on route to route conversion of toxicity factors. This policy conforms with the USEPA policy concerning route to route conversion of toxicity factors.
3 Although a CalEPA slope factor for chloroform exists, the USEPA believes there is a threshold effect for cancer. As such, an RfD based soil remediation standard is protective of both cancer and non-cancer health endpoints.
4 Although a CalEPA Slope Factor for 1,4-dichlorobenzene exists, there are questions about the study used to develop the slope factor. As such, the Department has decided not to develop an ingestion-dermal soil remediation standard for 1,4-dichlorobenzene using this slope factor.
5 Although a NJDWQI RfD for 1,1-dichloroethane exists, it is based on an inhalation route to route conversion. The Department's Site Remediation and Waste Management Program policy does not allow, except where warranted, for the development of soil remediation standards based on route-to-route conversion of toxicity factors. This policy conforms with the USEPA policy concerning route to route conversion of toxicity factors.
6 Although a PPRTV RfD for 1,2-dichloroethane exists, it is listed as an appendix value. PPRTV appendix values are based on a study(s) that has flaws as determined by the USEPA. It is the Department's Site Remediation and Waste Management Program policy not to use PPRTV appendix values to develop soil remediation standards.
7 Although a CalEPA slope factor for ethylbenzene exists, it is based on an inhalation route-to-route conversion. The Department's Site Remediation and Waste Management Program policy does not allow, except where warranted, for the development of soil remediation standards based on route-to-route conversion of toxicity factors. This policy conforms with the USEPA policy concerning route-to-route conversion of toxicity factors.
8 Although a CalEPA slope factor for methyl tert-butyl ether exists, there are questions about the study used to develop the slope factor. As such, the Department has decided not to develop an ingestion-dermal soil remediation standard for methyl tert-butyl ether using this slope factor.
9Although an NJDWQI RfD for 1,1,2,2-tetrachloroethane exists, the Department has decided to use an IRIS RfD to develop a non-cancer-based ingestion-dermal soil remediation standard as the IRIS RfD is based on a newer toxicology assessment.
10 Although an NJDWQI slope factor for tetrachloroethene exists, the Department has decided that the existing IRIS Slope Factor is a scientifically better toxicity value to develop a cancer-based ingestion-dermal soil remediation standard. The IRIS slope factor uses the newest PBPK models (extrapolating from an inhalation unit risk factor to an oral slope factor). An ingestion-dermal soil remediation standard for tetrachloroethene can also be developed using an IRIS RfD. The RfD uses the newest PBPK models (extrapolating from an inhalation RfC to oral RfD).
11Although an NJDWQI RfD for 1,2,4-trichlorobenzene exists, it is based on an inhalation route-to-route conversion. The Department's Site Remediation and Waste Management Program policy does not allow, except where warranted, for the development of soil remediation standards based on route-to-route conversion of toxicity factors. This policy conforms with the USEPA policy concerning route-to-route conversion of toxicity factors. In addition, a USEPA PPRTV slope factor for 1,2,4-trichlorobenzene is available, however the Slope Factor is based on a controversial mouse liver tumor study that many researchers have dismissed. The Department has decided not to develop an ingestion-dermal soil remediation standard based on the PPRTV slope factor.
12 Although an NJDWQI RfD for 1,1,1-trichloroethane exists, it is based on an inhalation route-to-route conversion. The Department's Site Remediation and Waste Management Program policy does not allow, except where warranted, for the development of soil remediation standards based on route-to-route conversion of toxicity factors. This policy conforms with USEPA policy concerning route-to-route conversion of toxicity factors.
13 Although an NJDWQI slope factor for 1,1,2-trichloroethane exists, the Department determined that the IRIS slope factor is a scientifically better toxicity value to develop a cancer-based ingestion-dermal soil remediation standard.
14 Although an NJDWQI slope factor for trichloroethene exists, the Department determined that the IRIS slope factor is a scientifically better toxicity value to develop a cancer-based ingestion-dermal soil remediation standard. The IRIS slope factor uses the newest PBPK models (extrapolating from an inhalation unit risk factor to an oral slope factor).
15 Although an IRIS RfD for 1,1,2-Trichloro-1,2,2-trifluoroethane exists, it is based on an inhalation route-to-route conversion. The Department's Site Remediation and Waste Management Program policy does not allow, except where warranted, for the development of soil remediation standards based on route-to-route conversion of toxicity factors. This policy conforms with USEPA policy concerning route-to-route conversion of toxicity factors.
16 Although an NJDWQI slope factor exists for vinyl chloride, the Department determined that the IRIS slope factor is a scientifically better toxicity value to develop a cancer-based ingestion-dermal soil remediation standard.
*17 Although an NJDWQI RfD (1994) for n-hexane exists, it is based on an inhalation route to route conversion. The Department's Site Remediation and Waste Management Program policy does not allow, except where warranted, for the development of soil remediation standards based on route to route conversion of toxicity factors. This policy conforms with USEPA policy concerning route to route conversion of toxicity factors.
Table 2-Soil Inhalation Toxicity Factors
| Contaminant | CAS No. | Soil Inhalation Recommendation | Soil Inhalation Toxicity Factor(s) |
| Acenaphthene | 83-32-9 | No inhalation-based toxicity factors are available18 | None |
| Acetone | 67-64-1 | No inhalation-based toxicity factors are available1 | None |
| No inhalation-based | |||
| Acetophenone | 98-86-2 | toxicity factors are available2 | None |
| Aldrin | 309-00-2 | No inhalation-based toxicity factors are available17 | None |
| Aluminum | 7429-90-5 | PPRTV RfC | PPRTV RfC (2006) 5E-03 mg/m3 |
| Anthracene | 120-12-7 | No inhalation-based toxicity factors are available18 | None |
| Antimony | 7440-36-0 | No inhalation-based toxicity factors are available19 | None |
| Arsenic | 7440-38-2 | IRIS IUR | IRIS IUR (1998) 4.3E-03 (ug/m3)-1 |
| No inhalation-based | |||
| Atrazine | 1912-24-9 | toxicity factors are available | None |
| Barium | 7440-39-3 | HEAST RfC | HEAST RfC (1997) 5E-04 mg/m3 |
| Benzaldehyde | 100-52-7 | No inhalation-based toxicity factors are available | None |
| Benzene | 71-43-2 | IRIS IUR IRIS RfC | IRIS IUR (2000) 7.8E-06 (ug/m3)-1 IRIS RfC (2003) 3E-02 mg/m3 |
| Benzo(a)anthracene | 56-55-3 | IRIS IUR (benzo(a) pyrene) adjusted for benzo(a)anthracene | IRIS IUR (2017) 6.0E-05 (ug/m3)-1 v (adjusted for benzo(a) anthracene) |
| Benzo(a)pyrene | 50-32-8 | IRIS IUR IRIS RfC | IRIS IUR (2017) 6.0E-04 (ug/m3)-1 IRIS RfC (2017) 2.0E-06 mg/m3 |
| Benzo(b)fluoranthene | 205-99-2 | IRIS IUR (benzo(a) pyrene) adjusted for benzo(b)fluoranthene | IRIS IUR (2017) 6.0E-05 (ug/m3)-1 (adjusted for benzo (b)fluoranthene) |
| Benzo(k)fluoranthene | 207-08-9 | IRIS IUR (benzo(a) pyrene) adjusted for benzo(k) fluoranthene | IRIS IUR (2017) 6.0E-06 (ug/m3)-1 (adjusted for benzo (k) fluoranthene) IRIS IUR (1998) |
| Beryllium | 7440-41-7 | IRIS IUR IRIS RfC | 2.4E-03 (ug/m3)-1 IRIS RfC (1998) 2E-05 mg/m3 |
| 1,1'-Biphenyl | 92-52-4 | No inhalation-based toxicity factors are available | None |
| Bis(2-chloroethoxy) methane | 111-91-1 | No inhalation-based toxicity factors are available | None |
| Bis(2-chloroethyl) ether | 111-44-4 | No inhalation-based toxicity factors are available17 | None |
| Bis(2-ethylhexyl) phthalate | 117-81-7 | No inhalation-based toxicity factors are available17 | None |
| Bromodichloromethane | 75-27-4 | No inhalation-based toxicity factors are available17 | None |
| No inhalation-based | |||
| Bromoform | 75-25-2 | toxicity factors are available17 | None |
| Bromomethane | 74-83-9 | IRIS RfC | IRIS RfC (1992) 5E-03 mg/m3 |
| 2-Butanone | 78-93-3 | IRIS RfC3 | IRIS RfC (2003) 5E+00 mg/m3 |
| Butylbenzylphthalate | 85-68-7 | No inhalation-based toxicity factors are available | None |
| Cadmium | 7440-43-9 | IRIS IUR ATSDR RfC | IRIS IUR (1992) 1.8E-03 (ug/m3)-1 ATSDR RfC (2013) 1E-05 mg/m3 |
| Caprolactam | 105-60-2 | CalEPA RfC | CalEPA RfC (2013) 2.2E-03 mg/m3 |
| Carbon disulfide | 75-15-0 | IRIS RfC | IRIS RfC (1995) 7E-01 mg/m3 |
| Carbon tetrachloride | 56-23-5 | IRIS IUR IRIS RfC | IRIS IUR (2010) 6E-06 (ug/m3)-1 IRIS RfC (2010) 1E-01 mg/m3 7 |
| Chlordane (alpha plus gamma mixture) | 57-74-9 | IRIS RfC | IRIS RfC (1998) 7E-04 mg/m3 |
| 4-Chloroaniline | 106-47-8 | No inhalation-based toxicity factors are available | None |
| Chlorobenzene | 108-90-7 | PPRTV RfC | PPRTV RfC (2006) 5E-02 mg/m3 |
| Chloroethane | 75-00-3 | IRIS RfC | IRIS RfC (1991) |
| ATSDR RfC No other inhalation- | ATSDR RfC (2013) | ||
| Chloroform | 67-66-3 | based toxicity factors are available17 | 1E+01 mg/m3 9.8E-02 mg/m3 |
| Chloromethane | 74-87-3 | IRIS RfC4 No inhalation-based | IRIS RfC (2001) 9E-02 mg/m3 |
| 2-Chloronaphthalene | 91-58-7 | toxicity factors are available | None |
| 2-Chlorophenol | 95-57-8 | No inhalation-based toxicity factors are available17 | None |
| Chrysene | 218-01-9 | IRIS IUR (benzo(a) pyrene) adjusted for chrysene | IRIS IUR (2017) 6.0E-07 (ug/m3)-1 (adjusted for chrysene) |
| Cobalt | 7440-48-4 | PPRTV IUR PPRTV RfC | PPRTV IUR (2008) 9E-03(ug/m3)-1 PPRTV RfC (2008) 6E-06 mg/m3 |
| Copper | 7440-50-8 | No inhalation-based toxicity factors are available5 | None |
| Cyanide | 57-12-5 | IRIS RfC | IRIS RfC (2010) 8E-04 mg/m3 |
| Cyclohexane | 110-82-7 | IRIS RfC | IRIS RfC (2003) 6E+00 mg/m3 |
| 4,4'-DDD | 72-54-8 | No inhalation-based toxicity factors are available17 | None |
| 4,4'-DDE | 72-55-9 | No inhalation-based toxicity factors are available17 | None |
| 4,4'-DDT | 50-29-3 | No inhalation-based toxicity factors are available17 | None |
| Dibenz(a,h)anthracene | 53-70-3 | IRIS IUR (benzo(a) pyrene) adjusted for dibenzo(a,h) anthracene | IRIS IUR (2017) 6.0E-04(ug/m3)-1 (adjusted for dibenzo(a,h) anthracene) |
| Dibromochloromethane | 124-48-1 | No inhalation-based toxicity factors are available17 | None PPRTV IUR (2006) |
| 1,2-Dibromo-3-chloropropane | 96-12-8 | PPRTV IUR IRIS RfC | 6E-03 (ug/m3)-1 IRIS RfC (1991) 2E-04 mg/m3 |
| 1,2-Dibromoethane | 106-93-4 | IRIS IUR IRIS RfC | IRIS IUR (2004) 6E-04 (ug/m3)-1 IRIS RfC (2004) 9E-03 mg/m3 |
| 1,2-Dichlorobenzene | 95-50-1 | HEAST RfC | HEAST RfC (1997) 2E-01 mg/m3 |
| 1,3-Dichlorobenzene | 541-73-1 | No inhalation-based toxicity factors are available | None |
| 1,4-Dichlorobenzene | 106-46-7 | IRIS RfC No other inhalationbased toxicity factors are available17 | IRIS RfC (1994) 8E-01 mg/m3 |
| 3,3'-Dichlorobenzidine | 91-94-1 | No inhalation-based toxicity factors are available | None |
| Dichlorodifluoromethane | 75-71-8 | No inhalation-based toxicity factors are available6 | None |
| 1,1-Dichloroethane | 75-34-3 | No inhalation-based toxicity factors are available7 | None |
| 1,2-Dichloroethane | 107-06-2 | PPRTV RfC No other inhalationbased toxicity factors are available17 | PPRTV RfC (2010) 7E-03 mg/m3 |
| 1,1-Dichloroethene | 75-35-4 | A soil inhalation remediation standard can be developed using an IRIS RfC with a Group C carcinogen factor | IRIS RfC (2002/2005) 2E-01 mg/m3 RfC Group C carcinogen factor 10 |
| cis-1,2-Dichloroethene | 156-59-2 | No inhalation-based toxicity factors are available | None |
| trans-1,2-Dichloroethene | 156-60-5 | No inhalation-based toxicity factors are available8 | None |
| 2,4-Dichlorophenol | 120-83-2 | No inhalation-based toxicity factors are available17 | None |
| 1,2-Dichloropropane | 78-87-5 | PPRTV IUR IRIS RfC | PPRTV IUR (2016) 3.7E-06 (ug/m3)-1 IRIS RfC (1991) 4E-03 mg/m3 |
| 1,3-Dichloropropene (cis and trans) | 542-75-6 | IRIS IUR IRIS RfC | IRIS IUR (2000) 4E-06 (ug/m3)-1 IRIS RfC (2000) 2E-02 mg/m3 |
| Dieldrin | 60-57-1 | No inhalation-based toxicity factors are available | None |
| Diethylphthalate | 84-66-2 | No inhalation-based toxicity factors are available17 | None |
| 2,4-Dimethylphenol | 105-67-9 | No inhalation-based toxicity factors are available17 | None |
| Di-n-butylphthalate | 84-74-2 | No inhalation-based toxicity factors are available17 | None |
| 2,4-Dinitrophenol | 51-28-5 | No inhalation-based toxicity factors are available17 | None |
| 2,4-Dinitrotoluene /2,6-Dinitrotoluene (mixture) | 25321-14 6 | No inhalation-based toxicity factors are available17 | None |
| Di-n-octylphthalate | 117-84-0 | No inhalation-based toxicity factors are available9 | None |
| 1,4-Dioxane | 123-91-1 | IRIS IUR IRIS RfC | IRIS IUR (2013) 5.0E-06 (ug/m3)-1 IRIS RfC (2013) 3E-02 mg/m3 |
| Endosulfan I and Endosulfan II (alpha and beta) | 115-29-7 | No inhalation-based toxicity factors are available17 | None |
| Endrin | 72-20-8 | No inhalation-based toxicity factors are available17 | None CalEPA IUR (2007) |
| Ethylbenzene | 100-41-4 | CalEPA IUR IRIS RfC | 2.5E-06 (ug/m3)-1 IRIS RfC (1991) 1E+00 mg/m3 |
| Extractable Petroleum Hydrocarbons (EPH) (Category 1) | various | No inhalation-based toxicity factors are available | None |
| Extractable Petroleum Hydrocarbons (EPH) (category 2) | various | No inhalation-based toxicity factors are available | None |
| Fluoranthene | 206-44-0 | No inhalation-based toxicity factors are available18 | None |
| Fluorene | 86-73-7 | No inhalation-based toxicity factors are available18 | None |
| alpha-HCH (alpha-BHC) | 319-84-6 | No inhalation-based toxicity factors are available17 | None |
| beta-HCH (beta-BHC) | 319-85-7 | No inhalation-based toxicity factors are available17 | None |
| Heptachlor | 76-44-8 | No inhalation-based toxicity factors are available17 | None |
| Heptachlor epoxide | 1024-57-3 | No inhalation-based toxicity factors are available17 | None |
| Hexachlorobenzene | 118-74-1 | No inhalation-based toxicity factors are available17 | None |
| Hexachloro-1,3-butadiene | 87-68-3 | No inhalation-based toxicity factors are available17 | None |
| Hexachlorocyclopentadiene | 77-47-4 | IRIS RfC | IRIS RfC (2001) 2E-04 mg/m3 |
| Hexachloroethane | 67-72-1 | IRIS RfC | IRIS RfC (2011) 3E-02 mg/m3 |
| n-Hexane | 110-54-3 | IRIS RfC | IRIS RfC (2005) 7E-01 mg/m3 |
| 2-Hexanone | 591-78-6 | IRIS RfC | IRIS RfC (2009) 3E-02 mg/m3 |
| Indeno(1,2,3,-cd) pyrene | 193-39-5 | IRIS IUR (benzo(a) pyrene) adjusted for indeno(1,2,3,-cd) pyrene. | IRIS IUR (2017) 6.0E-05 (ug/m3)-1 (adjusted for indeno(1,2,3,-cd) pyrene) |
| Isophorone | 78-59-1 | CalEPA RfC | CalEPA RfC (2001) 2E-00 mg/m3 |
| Isopropylbenzene | 98-82-8 | IRIS RfC | IRIS RfC (1997) 4E-01 mg/m3 |
| Lead | 7439-92-1 | No inhalation-based toxicity factors are available17 | None |
| Lindane (gamma-HCH) (gamma-BHC) | 58-89-9 | No inhalation-based toxicity factors are available17 | None |
| Manganese | 7439-96-5 | IRIS RfC | IRIS RfC (1993) 5E-05 mg/m3 |
| Mercury | 7439-97-6 | IRIS RfC | IRIS RfC (1995) 3E-04 mg/m3 |
| Methoxychlor | 72-43-5 | No inhalation-based toxicity factors are available17 | None |
| Methyl acetate | 79-20-9 | No inhalation-based toxicity factors are available | None |
| IRIS IUR (2011) | |||
| Methylene chloride | 75-09-2 | IRIS IUR IRIS RfC | 1E-08 (ug/m3)-1 IRIS RfC (2011) 6E-01 mg/m3 |
| 2-Methylnaphthalene | 91-57-6 | No inhalation-based toxicity factors are available18 | None |
| 4-Methyl-2-pentanone | 108-10-1 | IRIS RfC | IRIS RfC (2003) 3E+00 mg/m3 |
| 2-Methylphenol | 95-48-7 | No inhalation-based toxicity factors are available17 | None |
| 4-Methylphenol | 106-44-5 | No inhalation-based toxicity factors are available17 | None |
| Methyl tert-butyl ether (MTBE) | 1634-04-4 | CalEPA IUR IRIS RfC with a Group C carcinogen factor | CalEPA IUR (1999) 2.6E-07 (ug/m3)-1 IRIS RfC (1993) 3E+00 mg/m3 Group C carcinogen factor 10 |
| Naphthalene | 91-20-3 | CalEPA IUR IRIS RfC with a Group C carcinogen factor | CalEPA IUR (2011) 3.4E-05 (ug/m3)-1 IRIS RfC (1998) 3E-03 mg/m3 Group C carcinogen factor 10 |
| Nickel | 7440-02-0 | IRIS IUR CalEPA RfC | IRIS IUR (1987/2006) 2.4E-04 (ug/m3)-1 CalEPA RfC (2012) 1.4E-05 mg/m3 |
| 4-Nitroaniline | 100-01-6 | PPRTV RfC | PPRTV RfC (2009) 6E-03 mg/m3 |
| IRIS IUR (2009) | |||
| Nitrobenzene | 98-95-3 | IRIS IUR IRIS RfC | 4E-05 (ug/m3)-1 IRIS RfC (2009) |
| 9E-03 mg/m3 | |||
| No inhalation-based | |||
| N-Nitroso-di-n- propylamine | 621-64-7 | toxicity factors are available17 | None |
| No inhalation-based | |||
| N-Nitrosodiphenylamine | 86-30-6 | toxicity factors are available17 | None |
| No inhalation-based | |||
| 2,2'-Oxybis(1-choloropropane) | 108-60-1 | toxicity factors are available | None |
| No inhalation-based | |||
| Pentachlorophenol | 87-86-5 | toxicity factors are | None |
| available17 | |||
| Phenol | 108-95-2 | CalEPA RfC | CalEPA RfC (2000) 2E-01 mg/m3 |
| No inhalation-based | |||
| Polychlorinated biphenyls (PCBs) | 1336-36-3 | toxicity factors are | None |
| available17 No inhalation-based | |||
| Pyrene | 129-00-0 | toxicity factors are | None |
| available18 No inhalation-based | |||
| Selenium | 7782-49-2 | toxicity factors are | None |
| available No inhalation-based | |||
| Silver | 7440-22-4 | toxicity factors are | None |
| available17 | |||
| Styrene | 100-42-5 | IRIS RfC10 | IRIS RfC (1992) 1E+00 mg/m3 |
| No inhalation-based | |||
| Tertiary butyl alcohol (TBA) | 75-65-0 | toxicity factors are | None |
| available17 No inhalation-based | |||
| 1,2,4,5-Tetrachlorobenzene | 95-94-3 | toxicity factors are | None |
| available No inhalation-based | |||
| 2,3,7,8-Tetrachlorodibenzo-p-dioxin | 1746-01-6 | toxicity factors are | None |
| available No inhalation-based | |||
| 1,1,2,2-Tetrachloroethane | 79-34-5 | toxicity factors are | None |
| available17 | |||
| Tetrachloroethene (PCE) | 127-18-4 | IRIS IUR IRIS RfC | IRIS IUR (2012) 2.6E-07 (ug/m3)-1 IRIS RfC (2012) 4E-02 mg/m3 |
| No inhalation-based | |||
| 2,3,4,6-Tetrachlorophenol | 58-90-2 | toxicity factors are | None |
| available | IRIS RfC (2005) | ||
| Toluene | 108-88-3 | IRIS RfC | 5E+00 mg/m3 |
| No inhalation-based | |||
| Toxaphene | 8001-35-2 | toxicity factors are | None |
| available17 | |||
| 1,2,4-Trichlorobenzene | 120-82-1 | PPRTV RfC | PPRTV RfC (2009) 2E-03 mg/m3 |
| IRIS RfC (2007) | |||
| 1,1,1-Trichloroethane | 71-55-6 | IRIS RfC11 | 5E+00 mg/m3 |
| 1,1,2-Trichloroethane | 79-00-5 | No inhalation-based toxicity factors are available12 | None |
| IRIS IUR (2011) 4.1E- | |||
| Trichloroethene (TCE) | 79-01-6 | IRIS IUR IRIS RfC13 | 06 (ug/m3)-1 IRIS RfC (2011) 2E-03 mg/m3 |
| Trichlorofluoromethane | 75-69-4 | No inhalation-based toxicity factors are available14 | None |
| 2,4,5-Trichlorophenol | 95-95-4 | No inhalation-based toxicity factors are available17 | None |
| 2,4,6-Trichlorophenol | 88-06-2 | No inhalation-based toxicity factors are available17 | None |
| 1,1,2-Trichloro-1,2,2-trifluoroethane | 76-13-1 | PPRTV RfC | PPRTV RfC (2016) 5E+00 mg/m3 |
| 1,2,4-Trimethylbenzene | 95-63-6 | IRIS RfC | IRIS RfC (2016) 6E-02 mg/m3 |
| Vanadium | 7440-62-2 | ATSDR RfC | 1E-04 mg/m3 |
| IRIS IUR (2000) 4.4E- | |||
| Vinyl Chloride | 75-01-4 | IRIS IUR IRIS RfC15 | 06 (ug/m3)-1 IRIS RfC (2000) 1E-01 mg/m3 |
| Xylenes | 1330-20-7 | IRIS RfC | IRIS RfC (2003) 1.E-01 mg/m3 |
| Zinc | 7440-66-6 | No inhalation-based toxicity factors are available16 | None |
1 An ATSDR RfC exists for acetone using the results of the Stewart 1975 study. The USEPA IRIS notes that this study should only be used in the development of a short-term exposure RfC and not a long-term (chronic) exposure RfC.
2 A HEAST RfC exists for acetophenone, but a subsequent PPRTV review (2010) questions the use of the HEAST RfC.
3 A NJDWQI RfC exists for 2-butanone, but the IRIS RfC has been determined by the Department to be more appropriate. The existing NJDWQI RfC is based on a route-to-route conversion of a NJDWQI RfD. The Department's Site Remediation and Waste Management Program policy does not allow, except where warranted, for the development of soil remediation standards based on route-to-route conversion of toxicity factors. This policy conforms with USEPA policy concerning route-to-route conversion of toxicity factors.
4 A HEAST IUR exists for chloromethane, but a subsequent PPRTV review (2012) states that the use of the HEAST IUR is "Inadequate for an assessment of carcinogenic potential."
5 A CalEPA RfC that once existed for copper has been retracted by CalEPA.
6 A HEAST RfC and a PPRTV RfC exist for dichlorodifluoromethane. Both RfCs are derived using the same study (Prendergast 1967). The PPRTV is listed as an appendix value. The PPRTV RfC is listed as an appendix value because the Prendergast study was determined by the USEPA to have flaws. It is the Department's Site Remediation and Waste Management Program policy not to use PPRTV appendix values to develop soil remediation standards. As the HEAST RfC developed using the Prendergast study, the Department decided not to use this RfC in the development of a soil remediation standard.
7 A HEAST RfC exists for 1,1-dichloroethane, but a subsequent PPRTV review (2006) indicated that data were inadequate to derive a chronic exposure RfC for 1,1-dichloroethane. A CalEPA IUR also exists for 1,1-dichloroethane but is based on a route-to-route conversion of an oral study. The Department's Site Remediation and Waste Management Program policy does not allow, except where warranted, for the development of soil remediation standards based on route-to-route conversion of toxicity factors.
8A PPRTV RfC exists for trans-1,2-dichloroethene but a subsequent IRIS assessment (2010) stated "the available inhalation data from the Freund study are insufficient to support reference value derivation and RfC."
9 A 1985 USEPA IUR that once existed for di-n-octylphthalate has been retracted by the USEPA.
10 A HEAST 1991 IUR exists for styrene but USEPA NCEA does not recommend its use.
11 Although an NJDWQI RfC exists for 1,1,1-trichloroethane, the Department determined that the IRIS RfC is a scientifically better toxicity value to develop a non-cancer-based soil inhalation remediation standard.
12 Although a PPRTV RfC for 1,1,2-trichloroethane exists, it is listed as an appendix value. The PPRTV appendix value is based on a study that was determined by USEPA to have flaws. It is the Department's Site Remediation and Waste Management Program policy not to use PPRTV appendix values to develop soil remediation standards. An IRIS IUR also exists for 1,1,2-trichloroethane but is based on a route-to-route conversion of an oral study. The Department's Site Remediation and Waste Management Program policy does not allow, except where warranted, for the development of soil remediation standards based on route-to-route conversion of toxicity factors.
13 The IRIS RfC for trichloroethene is based on a route-to-route conversion of an ingestion study, which was determined to be acceptable by the USEPA as substantiated by additional evaluation including physiologically-based pharmacokinetic modeling.
14 A HEAST RfC exists for trichlorofluoromethane, but a subsequent PPRTV review (2009) indicated that data used to derive the RfC were inadequate.
15 The IRIS RfC for vinyl chloride is based on a route-to-route conversion of an ingestion study, which was determined to be acceptable by the USEPA as substantiated by additional evaluation including physiologically-based pharmacokinetic modeling.
16 A CalEPA RfC that once existed for zinc has been retracted by CalEPA.
*17There is an inhalation toxicity factor available for this contaminant, but it is based on a route-to-
route conversion of an oral study. The Department's Site Remediation and Waste Management Program policy does not allow, except where warranted with physiologically-based pharmacokinetic modeling, for the development of soil remediation standards based on route-to-route conversion of toxicity factors.
18The 2008 inhalation toxicity factor was based on an equivalency factor from Nisbet and LaGoy (1992). Nisbet and LaGoy did not conduct any original research and relied on studies using dermal application and subcutaneous injection, with one study using intrapulmonary administration (not inhalation). The Nisbet and LaGoy study develops TEFs for PAHs compared to BP. The Department did not use this study because it was not derived from an inhalation study.
19The former IRIS RfC was withdrawn.
Table 3--Indoor Air Toxicity Factors
| Contaminant | CAS No. | VI Recommendation | VI Toxicity Factor (s) |
| Acenaphthene | 83-32-9 | Not applicable No inhalation-based | Not applicable |
| Acetone | 67-64-1 | toxicity factors are available1 | None |
| Acetophenone | 98-86-2 | Not applicable | Not applicable |
| Aldrin | 309-00-2 | Not applicable | Not applicable |
| Aluminum | 7429-90-5 | Not applicable | Not applicable |
| Anthracene | 120-12-7 | Not applicable | Not applicable |
| Antimony | 7440-36-0 | Not applicable | Not applicable |
| Arsenic | 7440-38-2 | Not applicable | Not applicable |
| Atrazine | 1912-24-9 | Not applicable | Not applicable |
| Barium | 7440-39-3 | Not applicable | Not applicable |
| Benzaldehyde | 100-52-7 | Not applicable | Not applicable |
| Benzene | 71-43-2 | IRIS IUR | IRIS IUR (2000) |
| IRIS RfC | 7.8E-06 (ug/m3)-1 | ||
| IRIS RfC (2003) 3E-02 mg/m3 | |||
| Benzo(a)anthracene | 56-55-3 | Not applicable | Not applicable |
| Benzo(a)pyrene | 50-32-8 | Not applicable | Not applicable |
| Benzo(b)fluoranthene | 205-99-2 | Not applicable | Not applicable |
| Benzo(k)fluoranthene | 207-08-9 | Not applicable | Not applicable |
| Beryllium | 7440-41-7 | Not applicable | Not applicable |
| 1,1'-Biphenyl | 92-52-4 | Not applicable | Not applicable |
| Bis(2-chloroethoxy) methane | 111-91-1 | Not applicable | Not applicable |
| Bis(2-chloroethyl) ether | 111-44-4 | Not applicable | Not applicable |
| Bis(2-ethylhexyl) phthalate | 117-81-7 | Not applicable | Not applicable |
| Bromodichloromethane | 75-27-4 | No inhalation-based toxicity factors are available13 | None |
| No inhalation-based | |||
| Bromoform | 75-25-2 | toxicity factors are available13 | None |
| Bromomethane | 74-83-9 | IRIS RfC | IRIS RfC (1992) 5E-03 mg/m3 |
| 2-Butanone | 78-93-3 | VI standard can be developed using IRIS RfC2 | IRIS RfC (2003) |
| 5E+00 mg/m3 | |||
| Butylbenzylphthalate | 85-68-7 | Not applicable | Not applicable |
| Cadmium | 7440-43-9 | Not applicable | Not applicable |
| Caprolactam | 105-60-2 | Not applicable | Not applicable |
| Carbon disulfide | 75-15-0 | IRIS RfC | IRIS RfC (1995) 7E-01 mg/m3 |
| Carbon tetrachloride | 56-23-5 | IRIS IUR | IRIS IUR (2010) |
| IRIS RfC | 6E-06 (ug/m3)-1 IRIS RfC (2010) 1E-01 mg/m3 | ||
| Chlordane | 57-74-9 | Not applicable | Not applicable |
| (alpha plus gamma mixture) 4-Chloroaniline | 106-47-8 | Not applicable | Not applicable |
| Chlorobenzene | 108-90-7 | PPRTV RfC | PPRTV RfC (2006)5E-02 mg/m3 |
| Chloroethane | 75-00-3 | IRIS RfC | IRIS RfC (1991) 1E+01 mg/m3 |
| Chloroform | 67-66-3 | ATSDR RfC | ATSDR RfC (2013) |
| No other inhalationbased toxicity factors are available13 | 9.8E-02 mg/m3 | ||
| Chloromethane | 74-87-3 | IRIS RfC3 | IRIS RfC (2001) 9E-02 mg/m3 |
| 2-Chloronaphthalene | 91-58-7 | Not applicable | Not applicable |
| 2-Chlorophenol | 95-57-8 | Not applicable | Not applicable |
| Chrysene | 218-01-9 | Not applicable | Not applicable |
| Cobalt | 7440-48-4 | Not applicable | Not applicable |
| Copper | 7440-50-8 | Not applicable | Not applicable |
| Cyanide | 57-12-5 | Not applicable | Not applicable |
| Cyclohexane | 110-82-7 | IRIS RfC | IRIS RfC (2003) 6E+00 mg/m3 |
| 4,4'-DDD | 72-54-8 | Not applicable | Not applicable |
| 4,4'-DDE | 72-55-9 | Not applicable | Not applicable |
| 4,4'-DDT | 50-29-3 | Not applicable | Not applicable |
| Dibenz(a,h)anthracene | 53-70-3 | Not applicableNo inhalation-based | Not applicable |
| Dibromochloromethane | 124-48-1 | toxicity factors are available13 | None |
| 1,2-Dibromo-3-chloropropane | 96-12-8 | Not applicable | Not applicable |
| 1,2-Dibromoethane | 106-93-4 | IRIS IUR | IRIS IUR (2004) |
| IRIS RfC | 6E-04 (ug/m3)-1 IRIS RfC (2004) 9E-03 mg/m3 | ||
| 1,2-Dichlorobenzene | 95-50-1 | HEAST RfC | HEAST RfC (1997)2E-01 mg/m3 |
| No inhalation-based | |||
| 1,3-Dichlorobenzene | 541-73-1 | toxicity factors are available | None |
| 1,4-Dichlorobenzene | 106-46-7 | IRIS RfC | IRIS RfC (1996) |
| No other inhalationbased toxicity factors are available13 | 8E-01 mg/m3 | ||
| 3,3'-Dichlorobenzidine | 91-94-1 | Not applicableNo inhalation-based | Not applicable |
| Dichlorodifluoromethane | 75-71-8 | toxicity factors are available4 | None |
| No inhalation-based | |||
| 1,1-Dichloroethane | 75-34-3 | toxicity factors are available5 | None |
| 1,2-Dichloroethane | 107-06-2 | PPRTV RfC | PPRTV RfC (2010) |
| No other inhalationbased toxicity factors are available13 | 7E-03 mg/m3 | ||
| 1,1-Dichloroethene | 75-35-4 | IRIS RfC with a Group C carcinogen factor | IRIS RfC (2002/2005) |
| 2E-01 mg/m3 | |||
| Group C carcinogen factor 10 | |||
| No inhalation-based | |||
| cis-1,2-Dichloroethene | 156-59-2 | toxicity factors are available | None |
| No inhalation-based | |||
| trans-1,2-Dichloroethene | 156-60-5 | toxicity factors are available6 | None |
| 2,4-Dichlorophenol | 120-83-2 78-87-5 | PPRTV IUR | PPRTV IUR (2016) |
| IRIS RfC | 3.7E-06 (ug/m3)-1 | ||
| IRIS RfC (1991) 4E-03 mg/m3 | |||
| 1,3-Dichloropropene | 5422-75-6 | IRIS IUR | IRIS IUR (2000) |
| (cis and trans) | IRIS RfC | 4E-06 (ug/m3)-1 IRIS RfC (2000) 2E-02 mg/m3 | |
| Dieldrin | 60-57-1 | Not applicable | Not applicable |
| Diethylphthalate | 84-66-2 | Not applicable | Not applicable |
| 2,4-Dimethylphenol | 105-67-9 | Not applicable | Not applicable |
| Di-n-butylphthalate | 84-74-2 | Not applicable | Not applicable |
| 2,4-Dinitrophenol | 51-28-5 | Not applicable | Not applicable |
| 2,4-Dinitrotoluene /2,6-Dinitrotoluene(mixture) | 25321-146 | Not applicable | Not applicable |
| Di-n-octyl phthalate | 117-84-0 | Not applicable | Not applicable |
| 1,4-Dioxane | 123-91-1 | IRIS IUR | IRIS IUR (2013) |
| IRIS RfC | 5.0E-06 (ug/m3)-1 | ||
| IRIS RfC (2013) 3E-02 mg/m3 | |||
| Endosulfan I and Endosulfan II (alpha and beta) | 115-29-7 | Not applicable | Not applicable |
| Endrin | 72-20-8 | Not applicable | Not applicable |
| Ethylbenzene | 100-41-4 | CalEPA IUR | CalEPA IUR (2007) |
| IRIS RfC | 2.5E-06 (ug/m3)-1 | ||
| IRIS RfC (1991) 1E+00 mg/m3 | |||
| Extractable Petroleum Hydrocarbons (EPH) (Category 1) | various | Not applicable | Not applicable |
| Extractable Petroleum Hydrocarbons (EPH) (Category 2) | various | Not applicable | Not applicable |
| Fluoranthene | 206-44-0 | Not applicable | Not applicable |
| Fluorene | 86-73-7 | Not applicable | Not applicable |
| alpha-HCH (alpha-BHC) | 319-84-6 | Not applicable | Not applicable |
| beta-HCH (beta-BHC) | 319-85-7 | Not applicable | Not applicable |
| Heptachlor | 76-44-8 | Not applicable | Not applicable |
| Heptachlor epoxide | 1024-57-3 | Not applicable | Not applicable |
| Hexachlorobenzene | 118-74-1 | Not applicable | Not applicable |
| Hexachloro-1,3-butadiene | 87-68-3 | No inhalation-based toxicity factors are available13 | None |
| Hexachlorocyclopentadiene | 77-47-4 | Not applicable | Not applicable |
| Hexachloroethane | 67-72-1 | Not applicable | Not applicable |
| n-Hexane | 110-54-3 | IRIS RfC | IRIS RfC (2005) |
| 7E-01 mg/m3 | |||
| 2-Hexanone | 591-78-6 | Not applicable | Not applicable |
| Indeno(1,2,3,-cd) pyrene | 193-39-5 | Not applicable | Not applicable |
| Isophorone | 78-59-1 | Not applicable | Not applicable |
| Isopropylbenzene | 98-82-8 | Not applicable | Not applicable |
| Lead | 7439-92-1 | Not applicable | Not applicable |
| Lindane (gamma-HCH) (gamma-BHC) | 58-89-9 | Not applicable | Not applicable |
| Manganese | 7439-96-5 | Not applicable | Not applicable |
| Mercury | 7439-97-6 | IRIS RfC | IRIS RfC (1995) 3E-04 mg/m3 |
| Methoxychlor | 72-43-5 | Not applicableNo inhalation-based | Not applicable |
| Methyl acetate | 79-20-9 | toxicity factors are available | None |
| Methylene chloride | 75-09-2 | IRIS IUR | IRIS IUR (2011) |
| IRIS RfC | 1E-08 (ug/m3)-1 | ||
| IRIS RfC (2011)6E-01 mg/m3 | |||
| 2-Methylnaphthalene | 91-57-6 | Not applicable | Not applicable |
| 4-Methyl-2-pentanone | 108-10-1 | IRIS RfC | IRIS RfC (2003) |
| 3E +00 mg/m3 | |||
| 2-Methylphenol | 95-48-7 | Not applicable | Not applicable |
| 4-Methylphenol | 106-44-5 | Not applicable | Not applicable |
| Methyl tert-butyl ether (MTBE) | 1634-04-4 | CalEPA IUR | CalEPA IUR (1999) |
| IRIS RfC | 2.6E-07 (ug/m3)-1 | ||
| IRIS RfC (1993) | |||
| 3E +00 mg/m3 | |||
| Naphthalene | 91-20-3 | CalEPA IUR | CalEPA IUR (2004) |
| IRIS RfC with a Group C | 3.4E-05 (ug/m3)- | ||
| carcinogen factor | 1IRIS RfC (1998) 3E-03 mg/m3 Group C carcinogen | ||
| Nickel | 7440-02-0 | Not applicable | Not applicable |
| 4-Nitroaniline | 100-01-6 | Not applicable | Not applicable |
| Nitrobenzene | 98-95-3 | Not applicable | Not applicable |
| N-Nitroso-di-n propylamine | 621-64-7 | Not applicable | Not applicable |
| N-Nitrosodiphenylamine | 86-30-6 | Not applicable | Not applicable |
| 2,2'-Oxybis(1-choloropropane) | 108-60-1 | Not applicable | Not applicable |
| Pentachlorophenol | 87-86-5 | Not applicable | Not applicable |
| Phenol | 108-95-2 | Not applicable | Not applicable |
| Polychlorinated biphenyls (PCBs) | 1336-36-3 | Not applicable | Not applicable |
| Pyrene | 129-00-0 | Not applicable | Not applicable |
| Selenium | 7782-49-2 | Not applicable | Not applicable |
| Silver | 7440-22-4 | Not applicable | Not applicable |
| Styrene | 100-42-5 | VI standard can be developed using IRIS RfC7 | IRIS RfC (1993) |
| 1E +00 mg/m3 | |||
| No inhalation-based | |||
| Tertiary butyl alcohol (TBA) | 75-65-0 | toxicity factors are available13 | None |
| 1,2,4,5-Tetrachlorobenzene | 95-94-3 | Not applicable | Not applicable |
| 2,3,7,8-Tetrachlorodibenzo-p-dioxin | 1746-01-6 | Not applicableNo inhalation-based | Not applicable |
| 1,1,2,2-Tetrachloroethane | 79-34-5 | toxicity factors are available13 | None |
| Tetrachloroethene (PCE) | 127-18-4 | IRIS IUR | IRIS IUR (2012) |
| IRIS RfC | 2.6E-07 (ug/m3)-1 | ||
| IRIS RfC (2012) 4E-02 mg/m3 | |||
| 2,3,4,6-Tetrachlorophenol | 58-90-2 | Not applicable | Not applicable |
| Toluene | 108-88-3 | IRIS RfC | IRIS RfC (2005) |
| 5E +00 mg/m3 | |||
| Toxaphene | 8001-35-2 | Not applicable | Not applicable |
| 1,2,4-Trichlorobenzene | 120-82-1 | PPRTV RfC | PPRTV RfC (2009)2E-03 mg/m3 |
| 1,1,1-Trichloroethane | 71-55-6 | IRIS RfC8 | IRIS RfC (2007) |
| 5E +00 mg/m3 | |||
| No inhalation-based | |||
| 1,1,2-Trichloroethane | 79-00-5 | toxicity factors are available9 | None |
| Trichloroethene (TCE) | 79-01-6 | IRIS IUR | IRIS IUR (2011) |
| IRIS RfC130> | 4.1E-06 (ug/m3)-1 | ||
| IRIS RfC (2011) | |||
| 2E-03 mg/m3 | |||
| No inhalation-based | |||
| Trichlorofluoromethane | 75-69-4 | toxicity factors are available131> | None |
| 2,4,5-Trichlorophenol | 95-95-4 | Not applicable | Not applicable |
| 2,4,6-Trichlorophenol | 88-06-2 | Not applicable | Not applicable |
| 1,1,2-Trichloro-1,2,2-trifluoroethane | 76-13-1 | PPRTV RfC | PPRTV RfC (2016)5E+00 mg/m3 |
| 1,2,4-Trimethylbenzene | 95-63-6 | IRIS RfC | IRIS RfC (2016) 6E-02 mg/m3 |
| Vanadium | 7440-62-2 | Not applicable | Not applicable |
| Vinyl Chloride | 75-01-4 | IRIS IUR. | IRIS IUR (2000) |
| IRIS RfC132> | 4.4E-06 (ug/m3)-1 | ||
| IRIS RfC (2000) | |||
| 1E-01 mg/m3 | |||
| Xylenes | 1330-20-7 | IRIS RfC | IRIS RfC (2003)1.E-01 mg/m3 |
| Zinc | 7440-66-6 | Not applicable | Not applicable |
1 An ATSDR RfC exists for acetone using the results of the Stewart 1975 study. The USEPA IRIS notes that this study should only be used in the development of a short-term exposure RfC and not a long-term (chronic) exposure RfC.
2 A NJDWQI RfC exists for 2-butanone, but the IRIS RfC has been determined by the Department to be more appropriate. The existing NJDWQI RfC is based on a route-to-route conversion of a NJDWQI RfD. The Department's Site Remediation and Waste Management Program policy does not allow, except where warranted, for the development of indoor air remediation standards based on route-to-route conversion of toxicity factors. This policy conforms with the USEPA policy concerning route-to-route conversion of toxicity factors.
3 A HEAST IUR exists for chloromethane, but a subsequent PPRTV review (2012) states that the use of the HEAST IUR is "Inadequate for an assessment of carcinogenic potential."
4 A HEAST RfC and a PPRTV RfC exist for dichlorodifluoromethane. Both RfCs are derived using the same study (Prendergast 1967). The PPRTV is listed as an appendix value. The PPRTV RfC is listed as an appendix value because the Prendergast study was determined by the USEPA to have flaws. It is the Department's Site Remediation and Waste Management Program policy not to use PPRTV appendix values to develop remediation standards. As the HEAST RfC was developed using the Prendergast study data, the Department decided not to use this RfC in the development of a remediation standard.
5 A HEAST RfC exists for 1,1-dichloroethane, but a subsequent PPRTV review (2006) indicated that data were inadequate to derive a chronic exposure RfC for 1,1-dichloroethane. A CalEPA IUR also exists for 1,1-dichloroethane but is based on a route-to-route conversion of an oral study. The Department's Site Remediation and Waste Management Program policy does not allow, except where warranted, for the development of indoor air remediation standards based on route-to-route conversion of toxicity factors.
6A PPRTV RfC exists for trans-1,2-dichloroethene but a subsequent IRIS assessment (2010) stated "the available inhalation data from the Freund study are insufficient to support reference value derivation and RfC." 7 A HEAST 1991 IUR exists for styrene but the USEPA NCEA does not recommend its use.
8 Although an NJDWQI RfC exists for 1,1,1-trichloroethane, the Department determined that the IRIS RfC is a scientifically better toxicity value to develop a non-cancer-based soil inhalation remediation standard.
9 Although a PPRTV RfC for 1,1,2-trichloroethane exists, it is listed as an appendix value. The PPRTV appendix value is based on a study that was determined by the USEPA to have flaws. It is the Department's Site Remediation and Waste Management Program policy not to use PPRTV appendix values to develop remediation standards. An IRIS IUR also exists for 1,1,2-trichloroethane but is based on a route-to-route conversion of an oral study. The Department's Site Remediation and Waste Management Program policy does not allow, except where warranted, for the development of indoor air remediation standards based on route-to-route conversion of toxicity factors.
10 The IRIS RfC for trichloroethene is based on a route-to-route conversion of an ingestion study, which was determined to be acceptable by the USEPA as substantiated by additional evaluation including physiologically-based pharmacokinetic modeling.
11 A HEAST RfC exists for trichlorofluoromethane, but a subsequent PPRTV review (2009) indicated that data used to derive the RfC were inadequate.
12The IRIS RfC for vinyl chloride is based on a route-to-route conversion of an ingestion study, which was determined to be acceptable by the USEPA as substantiated by additional evaluation including physiologically-based pharmacokinetic modeling.
*13There is an inhalation toxicity factor available for this contaminant, but it is based on a route-to-route conversion of an oral study. The Department's Site Remediation and Waste Management Program policy does not allow, except where warranted with physiologically-based pharmacokinetic modeling, for the development of indoor air remediation standards based on route-to-route conversion of toxicity factors.
References
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NJDWQI (New Jersey Drinking Water Quality Institute). 1994. Maximum Contaminant Level Recommendation for Hazardous Contaminants in Drinking Water, Appendix A, Health-Based Maximum Contaminant Level Support Documents and Addenda. (A-280 Values).
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TPHCWG (Total Petroleum Hydrocarbon Working Group). 1997. Hayes, L.A., Youngren, S.H., and Nakles, D. V. TPHCWG Series: Development of Fraction Specific Reference Doses (RfDs) and Reference Concentrations (RfCs). Volume 4.
USEPA (United States Environmental Protection Agency). 2004. Risk Assessment Guidance for Superfund Volume I: Human Health Evaluation Manual (Part E, Supplemental Guidance for Dermal Risk Assessment) Final. OSWER 9285.7-02EP. July 2004.
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