01-017-11 Me. Code R. § 4

Current through 2024-51, December 18, 2024

Section 017-11-4 - Permitted Substances

1. Therapeutic Medications

Veterinarians may administer the following medications to participating horses provided that, on any day for which the horse is entered to race, the urine and/or blood concentrations are below the Maximum Allowable Concentrations listed in the table below. Administration of medications not described in this section is prohibited.

Therapeutic Medication	Maximum Allowable Concentration
Acepromazine	10 nanograms per milliliter as 2-(1-hydroxyethyl) promazine sulfoxide (HEPS) in urine
Albuterol	1 nanogram per milliliter of urine
Betamethasone	10 picograms per milliliter of plasma or serum
Butorphanol	300 nanograms of total butorphanol in urine or 2 nanograms of free butorphanol per milliliter of plasma or serum
Cetirzine	6 nanograms per milliliter of plasma or serum
Cimetidine	400 nanograms per milliliters of plasma or serum
Clenbuterol	140 picograms per milliliter or urine or Level of Detection in plasma or serum
Dantrolene	100 picograms per milliliter of 5-hydroxydantrolene in plasma or serum
Detomidine	2 nanograms per milliliter of carboxydetomidine in urine or 1 nanogram per milliliter in blood
Dexamethasone	5 picograms per milliliter of plasma or serum
Diclofenac	5 nanograms per milliliter of plasma or serum
Dimethyl sulfoxide (DMSO)	10 micrograms per milliliter of plasma or serum
Firocoxib	20 nanograms per milliliter of plasma or serum
Flunixin	20 nanograms per milliliter of plasma or serum
Furosemide	100 nanograms per milliliter of plasma or serum
Glycopyrrolate	3 picograms per milliliter of plasma or serum
Guaifenesin	12 nanograms per milliliter of plasma or serum
Isoflupredone	100 nanograms permilliliter of plasma or serum
Ketoprofen	2 nanograms per milliliter of plasma or serum
Lidocaine	20 picograms per milliliter of total 30H-lidocaine in plasma or serum
Mepivacaine	10 nanograms total hydroxymepivacaine per milliliter of urine or above the Level of Detection of mepivacaine in plasma or serum
Methocarbamol	1 nanogram per milliliter of plasma or blood
Methylprednisolone	100 picograms per milliliter of plasma or serum
Omeprazole	Omeprazole sulfide - 10 nanograms per milliliter of plasma or serum
Phenylbutazone	5 micrograms per milliliter of plasma or serum
Prednisolone	1 nanogram per milliliter of plasma or serum
Procaine penicillin (administration must be reported to the Commission)	25 nanograms per milliliter of plasma or serum
Ranitidine	40 nanograms per milliliter of plasma or serum
Triamcinolone	100 picograms per milliter of plasma or serum
Xylazine	200 picograms per milliliter of plasma or serum

2.Furosemide Program

A. Horses ineligible to participate in the Furosemide Program:

(1) Two year olds are not allowed on the Furosemide Program.

(2) Horses eligible to participate in the Maine Sire Stakes Program are not allowed on the Furosemide Program.

B.Furosemide

(1)Eligibility. In order to be eligible for the use of furosemide on race day, a horse must be certified as "Furosemide Eligible" by a veterinarian on a form approved by the Department. A copy of that certification must be on file in the Department office. The Commission Veterinarian may certify a horse as "furosemide eligible" based on a finding of a "good cause showing" of the need for the use of furosemide to treat the horse for Exercised Induced Pulmonary Hemorrhage (EIPH). A good cause showing may be determined by:

(a) The Commission Veterinarian attesting to the medical need for the therapeutic administration of furosemide to treat EIPH based on personal observation, or an endoscopic examination of the horse, and evaluation of the horse's medical condition by the Commission Veterinarian;

(b) A written statement by a veterinarian attesting to the medical need for the therapeutic administration of furosemide to treat EIPH based on personal observation, or an endoscopic examination of the horse, and evaluation of the horse's medical condition by that veterinarian; or

(c) The horse has raced on furosemide in its last race in another jurisdiction.

(2)Declaration. The trainer of a horse certified as "Furosemide Eligible" shall indicate that the horse is "Furosemide Eligible" on the declaration form each time the horse is entered to race. If the horse is racing with furosemide for the first time, the trainer shall indicate that on the declaration form. A trainer who violates this subsection shall be subject to a fine or suspension of their license, or both.

Each Association shall ensure that the official program correctly identifies all horses racing on the Furosemide Program. All horses racing on furosemide for the first time must be noted in the official program as "first time Lasix" at the bottom of the program page. Failure to provide an accurate official program shall be a Level Three violation of these rules.

(3)Administration of Furosemide

(a)Schedule. All horses entered to race on furosemide must report to the area within the paddock designated by the paddock judge for the administration of furosemide not less than three hours prior to the published post time for that horse's race.

The Commission Veterinarian shall establish a schedule for the administration of the furosemide.

(b)Procedures. Horses may be administered furosemide only by hypodermic injection by or under the supervision of the Commission Veterinarian.

(c)Permitted dosage. A horse eligible to use furosemide will be permitted a dosage equal to a minimum of 100 milligrams (2 cc.) and a maximum of 250 milligrams (5 cc.). The dosage must be administered no less than 3 hours and no more than 3 1/2 hours prior to the published post time for that horse's race. Any horse that is past the 3 hour mark for furosemide will be considered late for Lasix. The horse will be allowed to receive furosemide up to 10 minutes past the 3 hour mark with a warning or fine. After 10 minutes the horse will be ineligible to start.

(4)Log of Treated Horses. The Commission Veterinarian shall keep a log of the name of each horse given furosemide, the name of the trainer, and the time the furosemide was given.

(5)Removal from the furosemide list. A horse that has been eligible for the administration of furosemide may be removed from the list upon authorization from the Presiding Judge by the trainer completing an Off Lasix Form. This must be complete prior to the clearing of the official race program.

C.User fee. A user fee shall be paid by the trainer for each horse which races on furosemide. The fee shall be determined by the Department and shall be paid prior to the administration of the furosemide to offset the cost of the Furosemide Program. All funds collected shall be dedicated to the administration of the Furosemide Program. The Department shall consider the following criteria when establishing the fee for this program:

(1) Compensation of the Commission Veterinarian administering the furosemide;

(2) Cost of medication and medical supplies;

(3) Compensation of additional paddock personnel; and,

(4) Other reasonable administrative costs of the Furosemide Program.

D.Exercise Induced Pulmonary Hemorrhage Monitoring.

Whenever there is evidence that a participating horse has experienced Exercise Induced Pulmonary Hemorrhage (EIPH), the following procedures shall apply:

(1)First time. Any horse known to have bled externally from its nostrils or observed via endoscopic examination to have bled internally during a race or workout shall be subject to the following: The first time EIPH occurs the horse may not race for a period of eight days.

(2)Second Time. If a horse bleeds a second time, within 365 days of the first time, that horse shall be placed on the State Steward's List and prohibited from racing for a period of 30 days.

(3)Third Time. If a horse bleeds a third time, within 365 days of when the horse bled the first time, that horse shall be placed on the State Steward's List and prohibited from racing for a minimum of 90 days.

(4)Fourth Time. In the event a horse bleeds a fourth time, within 365 days of the first time, that horse shall be permanently prohibited from racing in this state.

(5)EIPH. The Judges and Department Veterinarian shall maintain a data base of all horses which they know to have experienced EIPH during a race.

3.Stacking of Non-Steroidal Anti-Inflammatory Drugs (NSAIDs)

The use of NSAIDs shall be governed by the following conditions:

A. Except as provided in this section relative to the phenylbutazone thresholds, NSAIDs shall be used in a manner consistent with the restrictions contained in the Uniform Classification Guidelines for Foreign Substances And Recommended Penalties Model Rule. January, 2018 (V.13.4) published by the Association of Racing Commissioners International. NSAIDs not listed in Section of this chapter shall not be present in a biological sample from a participating horse at the laboratory concentration of detection.

B. The presence of NSAIDs in a manner inconsistent with the Uniform Classification Guidelines for Foreign Substances And Recommended Penalties Model Rule. January, 2018 (V.13.4) published by the Association of Racing Commissioners International, as evidenced by a biological sample result, shall constitute prima facie evidence of violation of the trainer responsibilities. Use of withdrawal guidelines may not prevent a violation of this section. Adherence to those guidelines does not constitute a defense.

C. The presence of more than one NSAID may constitute a NSAID stacking violation consistent with the following restrictions:

(1) A Class 1 NSAID Stacking Violation (Penalty Class B) occurs when:

(a) Two non-steroidal anti-inflammatory drugs are found at individual levels determined to exceed the following restrictions:

(i)Diclofenac - 5 nanograms per milliliter of plasma or serum;

(ii)Firocoxib - 20 nanograms per milliliter of plasma or serum;

(iii)Flunixin - 20 nanograms per milliliter of plasma or serum;

(iv)Ketoprofen - 2 nanograms per milliliter of plasma or serum;

(v)Phenylbutazone - 5 micrograms per milliliter of plasma or serum; or

(vi)all other non-steroidal anti-inflammatory drugs - laboratory concentration of detection.

(b) Three or more non-steroidal anti-inflammatory drugs are found at individual levels determined to exceed the following restrictions:

(i)Diclofenac - 5 nanograms per milliliter of plasma or serum;

(ii)Firocoxib - 20 nanograms per milliliter of plasma or serum;

(iii)Flunixin - 3 nanograms per milliliter of plasma or serum;

(iv)Ketoprofen - 1 nanograms per milliliter of plasma or serum;

(v)Phenylbutazone - 0.5 micrograms per milliliter of plasma or serum; or

(vi)all other non-steroidal anti-inflammatory drugs - laboratory concentration of detection.

(2) A Class 2 NSAID Stacking Violation (Penalty Class C) occurs when:

(a) Any one substance noted in Subsection (1)(a) above is found in excess of the restrictions contained therein in combination with any one of the following substances at levels below the restrictions so noted but in excess of the following levels:

(i)Flunixin - 3 nanograms per milliliter of plasma or serum;

(ii)Ketoprofen - 1 nanogram per milliliter of plasma or serum; or

(iii)Phenylbutazone - 0.5 micrograms per milliliter of plasma or serum;

(3) A Class 3 NSAID Stacking Violation (Penalty Class C, fines only) occurs when:

(a) Any combination of two of the following non-steroidal antiinflammatory drugs are found at or below the restrictions in Subsection (1) (a) (i through vi) above but in excess of the noted restrictions:

(i)Flunixin - 3 nanograms per milliliter of plasma or serum;

(ii)Ketoprofen - 1 nanogram per milliliter of plasma or serum; or

(iii)Phenylbutazone - 0.5 micrograms per milliliter of plasma or serum;

(4) Any horse to which a NSAID has been administered shall be subject to having a blood and/or urine sample(s) taken at the direction of the Department Veterinarian to determine the quantitative NSAID level(s) and/or the presence of other drugs which may be present in the blood or urine sample(s).

4.Other Permitted Substances

Liniments, antiseptics, antibiotics, ointments, leg paints, washes, and other products commonly used in the daily care of horses may be administered by a person, other than a licensed veterinarian if:

A. The treatment does not include any drug, medication, or substance otherwise prohibited by Section 2 of this chapter;

B. The treatment is not injected, and

C. The person is acting under the jurisdiction of a licensed trainer.

01-017 C.M.R. ch. 11, § 4