Del. Admin. Code tit. 16, Department of Health and Social Services, Division of Public Health, Health Promotion and Disease Prevention, 4202, app I
1. State of Delaware - List of Reportable Diseases/Conditions
AIDS / HIV Stage III (S)
Acute flaccid myelitis
Alpha gal syndrome
Amebiasis
Anaplasmosis
Anthrax (T)
Arboviral human infections:
Anaplasmosis
Cache Valley virus disease
California encephalitis virus disease
California serogroup virus diseases
Chikungunya virus disease
Colorado tick fever virus disease
Eastern equine encephalitis virus disease
Jamestown Canyon virus disease
Japanese encephalitis virus disease
Keystone virus disease
La Crosse virus disease
Powassan virus disease
Snowshoe hare virus disease
St. Louis encephalitis virus disease
Tick-borne encephalitis viruses
Trivittatus virus disease
West Nile virus disease
Western equine encephalitis virus disease
Venezuelan equine encephalitis virus
Zika virus disease
Other Arboviral diseases, not otherwise specified
Babesiosis
Botulism (T)
Brucellosis (T)
Campylobacteriosis
Candida auris
Carbapenemase-Producing Organisms (CPO)
Carbon monoxide poisoning
Chancroid (S)
Chickenpox (Varicella)
Chlamydia (S)
Cholera (toxigenic Vibrio cholerae 01 or 0139) (T)
Coccidioidomycosis
Coronavirus, novel (novel coronavirus causing severe acute respiratory disease including the 2019 novel coronavirus disease [COVID-19], severe acute respiratory syndrome-associated coronavirus disease [SARS-CoV], and Middle East Respiratory Syndrome [MERS-CoV]) (T)
Creutzfeldt-Jakob Disease (T)
Cronobacter infection
Cryptosporidiosis
Cyclosporiasis
Cytomegalovirus (neonatal only)
Dengue virus infections (T)
Diphtheria (T)
Ehrlichiosis
Encephalitis
Enterobacteriaceae, carbapenem-resistant (invasive or urine only) (A)
Escherichia coli, Shigatoxin producing (STEC) (T)
ESBL B-lactamases-invasive only (A)
Foodborne Disease Outbreak (T)
Free living amebae infections
Giardiasis
Glanders (T)
Gonorrhea (S)
Granuloma inguinale (S)
Guillain-Barre
Haemophilus influenzae, invasive
Hansen's Disease (Leprosy)
Hantavirus (T)
Hemolytic Uremic Syndrome (T)
Hepatitis A (T)
Hepatitis B
Hepatitis C
Hepatitis Other
Herpes, congenital (S)
Herpes, genital (S)
Histoplasmosis
HIV (S)
Human Papillomavirus (S)
Influenza
Influenza-associated pediatric mortality (T)
Kawasaki Syndrome
Lead, child blood, all test results
Legionellosis
Leptospirosis
Listeriosis
Lyme Disease
Lymphogranuloma venereum (S)
Malaria
Measles (T)
Melioidosis
Meningitis, Aseptic
Meningitis, Bacterial other
Meningococcal disease (Neisseria meningitidis) (T)
Mpox virus infection (T)
Mumps (T)
Norovirus
Nosocomial (Healthcare-Associated) Disease Outbreak (T)
Pelvic Inflammatory Disease (N. gonorrhoeae, C. trachomatis, or unspecified) (S)
Pertussis (T)
Plague (T)
Poliomyelitis (T)
Psittacosis
Q Fever
Rabies (human and animal) (T)
Respiratory Syncytial virus-associated deaths (RSV)
Reye Syndrome
Rheumatic Fever
Ricin Toxin (T)
Rickettsial Disease
Rubella (including congenital, which is rapidly reportable [T])
Salmonellosis
Shigellosis
Silicosis
Smallpox (T)
Spotted fever rickettsiosis
Staphylococcal aureus, Vancomycin Intermediate or Resistant (VISA, VRSA) (T)
Staphylococcal Enterotoxin (T)
Streptococcal Disease, invasive
Streptococcus pneumoniae, invasive (A)
Syphilis, all stages (S)
Tetanus (T)
Toxic Shock Syndrome (Streptococcal or Staphylococcal)
Toxoplasmosis
Trichinellosis
Tuberculosis (T)
Tularemia (T)
Typhoid Fever (T)
Typhus Fever (endemic flea borne, louse borne, tick borne)
Vaccine Adverse Reaction
Vancomycin resistant Enterococcus, invasive only
Vibrio, non-cholera
Viral Hemorrhagic Fevers (T)
Waterborne Disease Outbreaks (T)
Yellow Fever (T)
Yersiniosis
2. Reporting timeframe
(T) - call or email within 4 hours
(S) - sexually transmitted disease, report required within 24 hours
(A) - Drug-Resistant Organisms required to be reported within 48 hours
All others - report required within 48 hours
Del. Admin. Code tit. 16, Department of Health and Social Services, Division of Public Health, Health Promotion and Disease Prevention, 4202, app I
12 DE Reg. 1418 (05/01/09)
17 DE Reg. 320 (9/1/2013)
23 DE Reg. 665 (2/1/2020)
24 DE Reg. 791 (2/1/2021)
27 DE Reg. 863 (5/1/2024) (Final)