Chromatid-type aberration is structural chromosome damage expressed as breakage of single chromatids or breakage and reunion between chromatids.
Chromosome-type aberration is structural chromosome damage expressed as breakage, or breakage and reunion, of both chromatids at an identical site.
Endoreduplication is a process in which after an S period of DNA replication, the nucleus does not go into mitosis but starts another S period. The result is chromosomes with 2,4,8,...chromatids.
Gap is an achromatic lesion smaller than the width of one chromatid, and with minimum misalignment of the chromatids.
Numerical aberration is a change in the number of chromosomes from the normal number characteristic of the animals utilized.
Polyploidy is a multiple of the haploid chromosome number (n) other than the diploid number (i.e., 3n, 4n and so on).
Structural aberration is a change in chromosome structure detectable by microscopic examination of the metaphase stage of cell division, observed as deletions and fragments, intrachanges or interchanges.
Chemical | CAS No. |
Triethylenemelamine | [CAS no. 51-18-3] |
Ethyl methanesulphonate | [CAS no. 62-50-0] |
Ethyl nitrosourea | [CAS no. 759-73-9] |
Mitomycin C | [CAS no. 50-07-7] |
Cyclophosphamide (monohydrate) | [CAS no. 50-18-0] [CAS no. 6055-19-2] |
40 C.F.R. §799.9538