21 C.F.R. § 1308.14

Current through November 30, 2024

Section 1308.14 - Schedule IV

(a) Schedule IV shall consist of the drugs and other substances, by whatever official name, common or usual name, chemical name, or brand name designated, listed in this section. Each drug or substance has been assigned the DEA Controlled Substances Code Number set forth opposite it.

(b)Narcotic drugs. Unless specifically excepted or unless listed in another schedule, any material, compound, mixture, or preparation containing any of the following narcotic drugs, or their salts calculated as the free anhydrous base or alkaloid, in limited quantities as set forth below:

(1) Not more than 1 milligram of difenoxin and not less than 25 micrograms of atropine sulfate per dosage unit	9167
(2) Dextropropoxyphene (alpha-(+)-4-dimethylamino-1,2-diphenyl-3-methyl-2-propionoxybutane)	9278
(3) 2-[(dimethylamino)methyl]-1-(3-methoxyphenyl)cyclohexanol, its salts, optical and geometric isomers and salts of these isomers (including tramadol)	9752

(c)Depressants. Unless specifically excepted or unless listed in another schedule, any material, compound, mixture, or preparation which contains any quantity of the following substances, including its salts, isomers, and salts of isomers whenever the existence of such salts, isomers, and salts of isomers is possible within the specific chemical designation:

(1) Alfaxalone	2731
(2) Alprazolam	2882
(3) Barbital	2145
(4) Brexanolone	2400
(5) Bromazepam	2748
(6) Camazepam	2749
(7) Carisoprodol	8192
(8) Chloral betaine	2460
(9) Chloral hydrate	2465
(10) Chlordiazepoxide	2744
(11) Clobazam	2751
(12) Clonazepam	2737
(13) Clorazepate	2768
(14) Clotiazepam	2752
(15) Cloxazolam	2753
(16) Daridorexant	2410
(17) Delorazepam	2754
(18) Diazepam	2765
(19) Dichloralphenazone	2467
(20) Estazolam	2756
(21) Ethchlorvynol	2540
(22) Ethinamate	2545
(23) Ethyl loflazepate	2758
(24) Fludiazepam	2759
(25) Flunitrazepam	2763
(26) Flurazepam	2767
(27) Fospropofol	2138
(28) Halazepam	2762
(29) Haloxazolam	2771
(30) Ketazolam	2772
(31) Lemborexant	2245
(32) Loprazolam	2773
(33) Lorazepam	2885
(34) Lormetazepam	2774
(35) Mebutamate	2800
(36) Medazepam	2836
(37) Meprobamate	2820
(38) Methohexital	2264
(39) Methylphenobarbital (mephobarbital)	2250
(40) Midazolam	2884
(41) Nimetazepam	2837
(42) Nitrazepam	2834
(43) Nordiazepam	2838
(44) Oxazepam	2835
(45) Oxazolam	2839
(46) Paraldehyde	2585
(47) Petrichloral	2591
(48) Phenobarbital	2285
(49) Pinazepam	2883
(50) Prazepam	2764
(51) Quazepam	2881
(52) Remimazolam	2846
(53) Suvorexant	2223
(54) Temazepam	2925
(55) Tetrazepam	2886
(56) Triazolam	2887
(57) Zaleplon	2781
(58) Zolpidem	2783
(59) Zopiclone	2784
(60) Zuranolone	2420

(d) [Reserved]

(e)Lorcaserin. Any material, compound, mixture, or preparation which contains any quantity of the following substances, including its salts, isomers, and salts of such isomers, whenever the existence of such salts, isomers, and salts of isomers is possible:

(1) Lorcaserin

1625

(f)Stimulants. Unless specifically excepted or unless listed in another schedule, any material, compound, mixture, or preparation which contains any quantity of the following substances having a stimulant effect on the central nervous system, including its salts, isomers and salts of isomers:

(1) Cathine ((+)-norpseudoephedrine)	1230
(2) Diethylpropion	1610
(3) Fencamfamin	1760
(4) Fenproporex	1575
(5) Mazindol	1605
(6) Mefenorex	1580
(7)Modafinil	1680
(8) Pemoline (including organometallic complexes and chelates thereof)	1530
(9) Phentermine	1640
(10) Pipradrol	1750
(11) Serdexmethylphenidate	1729
(12) Sibutramine	1675
(13) Solriamfetol (2-amino-3-phenylpropyl carbamate; benzenepropanol, beta-amino-, carbamate (ester))	1650
(14) SPA ((-)-1-dimethylamino- 1,2-diphenylethane)	1635

(g)Other substances. Unless specifically excepted or unless listed in another schedule, any material, compound, mixture or preparation which contains any quantity of the following substances, including its salts:

(1) Pentazocine	9709
(2) Butorphanol (including its optical isomers)	9720
(3) Eluxadoline (5-[[[(2S)-2-amino-3-[4-aminocarbonyl)-2,6-dimethylphenyl]-1-oxopropyl][( 1S)-1-(4-phenyl-1H-imidazol-2-yl)ethyl]amino]methyl]-2-methoxybenzoic acid) (including its optical isomers) and its salts, isomers, and salts of isomers (9725).

21 C.F.R. §1308.14

39 FR 22143, June 20, 1974

84 FR 27943 , 27947, 6/17/2019; 84 FR 60333 , 11/8/2019; 85 FR 19391 , 4/7/2020; 85 FR 63019 , 10/6/2020; 86 FR 24492 , 5/7/2021; 87 FR 20318 , 4/7/2022; 87 FR 78859 , 12/23/2022; 88 FR 74352 , 10/31/2023

For FEDERAL REGISTER citations affecting §1308.14, see the List of CFR Sections Affected, which appears in the Finding Aids section of the printed volume and at www.govinfo.gov.