21 C.F.R. § 556.113

Current through October 31, 2024
Section 556.113 - Ceftiofur
(a)Acceptable daily intake and acute reference dose -
(1)Acceptable daily intake (ADI). The ADI for total residue of ceftiofur is 30 [MICRO]g/kg of body weight per day.
(2)Acute reference dose (ARfD). The ARfD for total residue of ceftiofur is 0.830 mg/kg of body weight.
(b)Tolerances. The tolerances for desfuroylceftiofur (marker residue) are:
(1)Cattle.
(i) Kidney (target tissue): 0.4 ppm.
(ii) Liver: 2 ppm.
(iii) Muscle: 1 ppm.
(iv) Milk: 0.1 ppm.
(2)Chickens and turkeys. Edible tissues (excluding eggs): Not required.
(3)Goats.
(i) Kidney (target tissue): 8 ppm.
(ii) Liver: 2 ppm.
(iii) Muscle: 1 ppm.
(iv) Milk: 0.1 ppm.
(4)Sheep. Edible tissues (excluding milk): Not required.
(5)Swine.
(i) Kidney (target tissue): 0.25 ppm.
(ii) Liver: 3 ppm.
(iii) Muscle: 2 ppm.
(c)Related conditions of use. See §§ 522.313a , 522.313b , 522.313c , and 526.313 of this chapter.

21 C.F.R. §556.113

84 FR 32993 , 9/9/2019