Section 529.1186 - Isoflurane(a)Specifications. The drug is a clear, colorless, stable liquid.(b)Sponsors. See Nos. 017033, 054771, and 065085 in § 510.600(c) of this chapter.(c)Conditions of use. Administer by inhalation: (1)Amount - (i)Horses: For induction of surgical anesthesia: 3 to 5 percent isoflurane (with oxygen) for 5 to 10 minutes. For maintenance of surgical anesthesia: 1.5 to 1.8 percent isoflurane (with oxygen).(ii)Dogs: For induction of surgical anesthesia: 2 to 2.5 percent isoflurane (with oxygen) for 5 to 10 minutes. For maintenance of surgical anesthesia: 1.5 to 1.8 percent isoflurane (with oxygen).(2)Indications for use. For induction and maintenance of general anesthesia in horses and dogs.(3)Limitations. Do not use in horses intended for human consumption. Federal law restricts this drug to use by or on the order of a licensed veterinarian.51 FR 594, Jan. 7, 1986, as amended at 54 FR 23472, June 1, 1989; 58 FR 17346, Apr. 2, 1993; 59 FR 44315, Aug. 29, 1994; 60 FR 40456, Aug. 9, 1995; 63 FR 8122, Feb. 18, 1998; 63 FR 24106, May 1, 1998; 66 FR 17510 , Apr. 2, 2001; 71 FR 43967 , Aug. 3, 2006; 74 FR 68530 , Dec. 28, 2009; 76 FR 16533 , Mar. 24, 2011; 78 FR 14669 , Mar. 7, 2013; 78 FR 17868 , Mar. 25, 2013; 80 FR 18776 , Apr. 8, 2015; 87 FR 58963 , Sept. 29, 2022; 89 FR 14411 , Feb. 27, 2024; 89 FR 42360 , May 15, 2024 82 FR 12170 , 3/13/2017; 87 FR 58963 , 9/29/2022; 89 FR 14411 , 2/27/2024; 89 FR 42360 , 5/15/2024