STATE OF CALIFORNIA | GRAY DAVIS, GOVERNOR | ||
DEPARTMENT OF INDUSTRIAL RELATIONS | |||
Industrial Medical Council | |||
395 Oyster Point Boulevard, 1st Floor, Wing C | ADDRESS REPLY TO: | ||
South San Francisco, CA 94080 | |||
P.O. Box 8888 | |||
San Francisco, CA 94128-8888 |
Guidelines For Immunologic Testing Adopted March 17, 1994
Laboratory testing of immunologic function is appropriate and necessary in the evaluation of industrial injuries but only in selected cases.
Immunologic function testing falls into four general categories:
Category I: Allergy To A Specific Chemical Agent
Testing shall be done only when:
Testing shall not be done for chemical agents to which the worker has not been exposed.
The purpose of Category I is to confirm that the worker is allergic and reactive to a specific chemical agent. The presence of a laboratory test showing reactivity does not in itself indicate physical disability unless there also are subjective symptoms and/or objective findings of physical impairment which are consistent with such reactivity. Many people have positive reactivity tests but do not have clinical disease. Testing methods must be for the specific chemical agent. They may be blood tests for antibodies, skin tests or special tests such as lymphocyte reactivity to beryllium.
Category II: Tendency To React To Common Allergens
This testing is of very limited use: It is allowable only when the clinical findings (e.g., sneezing, nasal obstruction or wheezing) could be due to either workplace agent or non-industrial exposure. Testing may be of the blood (IgE, RAST) or of the skin (patch, scratch or intradermal).
Category III: Testing Of Function Of The Immune System
In unusual circumstances (e.g., occupational exposures to ionizing radiation or chemotherapeutic agents), direct clinically significant damage to the immune system may occur and be relevant to the assessment of occupationally related disability. Many chemical agents other than chemotherapeutic drugs have been shown to produce subtle effects on the immune system in research studies. However, such subtle effects do not cause work-related disability and cannot be the basis for laboratory testing.
In the unusual circumstance in which the need for immune testing occurs, such testing shall involve some or all the following:
Cal. Code Regs. Tit. 8, § 47
2. Amendment of NOTE filed 4-14-2000; operative 5-14-2000 (Register 2000, No. 15).
3. Change without regulatory effect amending section filed 7-12-2001 pursuant to section 100, title 1, California Code of Regulations (Register 2001, No. 28). Pursuant to this filing, material adopted pursuant to the Administrative Procedure Act that had previously been incorporated by reference in the California Code of Regulations was instead printed in full in the California Code of Regulations.
4. Amendment filed 1-13-2009; operative 2-17-2009 (Register 2009, No. 3).
Note: Authority cited: Section 139.2(j)(2), Labor Code. Reference: Sections 139.2(j)(2), 4060, 4061 and 4062, Labor Code.
2. Amendment of Note filed 4-14-2000; operative 5-14-2000 (Register 2000, No. 15).
3. Change without regulatory effect amending section filed 7-12-2001 pursuant to section 100, title 1, California Code of Regulations (Register 2001, No. 28). Pursuant to this filing, material adopted pursuant to the Administrative Procedure Act that had previously been incorporated by reference in the California Code of Regulations was instead printed in full in the California Code of Regulations.
4. Amendment filed 1-13-2009; operative 2-17-2009 (Register 2009, No. 3).