Section 69403.14 - Ototoxicity(a) The ototoxicity hazard trait is defined as the occurrence of adverse effects on the structure or function of the inner ear or the vestibulo-cochlear nerve, or auditory portions of the central nervous system, which could result in temporary or permanent disturbances of hearing, balance, or both following exposure to a chemical substance.(b) Toxicological endpoints for ototoxicity include, but are not limited to those indicating: hearing impairment; abnormal balance; changes to cellular components of the inner ear; change in auditory response or electrical activity in the vestibulo-cochlear nerve or auditory areas of the brain.(c) Other relevant ototoxicity data include but are not limited to: in vitro indications of ototoxicity; structural or mechanistic similarity to other chemical substances that are ototoxic.Cal. Code Regs. Tit. 22, § 69403.14
1. New section filed 12-20-2011; operative 1-29-2012 (Register 2011, No. 51). Note: Authority cited: Sections 25256.1 and 59012, Health and Safety Code. Reference: Sections 25256.1 and 59012, Health and Safety Code.
1. New section filed 12-20-2011; operative 1-29-2012 (Register 2011, No. 51).