Ex Parte Popovic et alDownload PDFPatent Trial and Appeal BoardJan 31, 201914361943 (P.T.A.B. Jan. 31, 2019) Copy Citation UNITED STA TES p A TENT AND TRADEMARK OFFICE APPLICATION NO. FILING DATE FIRST NAMED INVENTOR 14/361,943 05/30/2014 Aleksandra Popovic 24737 7590 02/04/2019 PHILIPS INTELLECTUAL PROPERTY & STANDARDS 465 Columbus A venue Suite 340 Valhalla, NY 10595 UNITED STATES DEPARTMENT OF COMMERCE United States Patent and Trademark Office Address: COMMISSIONER FOR PATENTS P.O. Box 1450 Alexandria, Virginia 22313-1450 www .uspto.gov ATTORNEY DOCKET NO. CONFIRMATION NO. 2011P02286WOUS 2909 EXAMINER IP,JASONM ART UNIT PAPER NUMBER 3793 NOTIFICATION DATE DELIVERY MODE 02/04/2019 ELECTRONIC Please find below and/or attached an Office communication concerning this application or proceeding. The time period for reply, if any, is set in the attached communication. Notice of the Office communication was sent electronically on above-indicated "Notification Date" to the following e-mail address(es): patti. demichele@Philips.com marianne.fox@philips.com katelyn.mulroy@philips.com PTOL-90A (Rev. 04/07) UNITED STATES PATENT AND TRADEMARK OFFICE BEFORE THE PATENT TRIAL AND APPEAL BOARD Ex parte ALEKSANDRA POPOVIC, HAYTHRAM ELHAWARY, and CHRISTOPHER STEPHEN HALL 1 Appeal 2017-011019 Application 14/361,943 Technology Center 3700 Before FRANCISCO C. PRATS, JOHN E. SCHNEIDER, and DAVID COTTA, Administrative Patent Judges. SCHNEIDER, Administrative Patent Judge. DECISION ON APPEAL This is an appeal2 under 35 U.S.C. § 134 of the Examiner's rejection of claims to a system and method for guiding surgical robots which have been rejected as directed to non-statutory subject matter, as anticipated, and as obvious. We have jurisdiction under 35 U.S.C. § 6(b ). 1 Appellants identify KONINKLIJKE PHILLIPS N.V., as the real party in interest. Appeal Br. 4. 2 We have considered and herein refer to the Specification filed May 30, 2014 ("Spec."); Final Office Action mailed Dec. 1, 2016 ("Final Act."); Appeal Brief filed Apr 25, 2017 ("Appeal Br."); Examiner's Answer mailed June 27, 2017 ("Ans."); and Reply Brief, filed Aug. 25, 2017 ("Reply Br."). Appeal2017-011019 Application 14/361,943 We AFFIRM-IN-PART. STATEMENT OF THE CASE Coronary bypass surgery is a procedure in which a diseased coronary artery is abridged using an artery grafted elsewhere in the body. In minimally invasive bypass surgery, access to arteries is limited by the following factors: 1) Arteries are covered with fatty tissue or may run intramyocardially which makes them invisible in endoscope images; and 2) Due to limited motion permitted through ports, it is difficult to manually reach specific areas of the heart. These factors pose limitations for use of intraoperative [ ultrasound] in minimally invasive bypass surgery. Spec. ,r 1. The Specification describes a system and method for robotically guiding ultrasound probes for surgical imaging. Id. Claims 1-25 are on appeal. Claims 1 and 14 are representative and read as follows: 1. A system for surgical robotic guidance, compnsmg: a robotic system having a robot configured to pass to a target through a port, the robotic system including a visual component employed in guiding the robot along a path to a location, the location being defined in accordance with a position and orientation of the robot; and an ultrasonic probe guided by the robot to the location to permit engagement of the probe to collect ultrasonic images at the location. 14. A method for surgical robotic guidance, compnsmg: introducing a robot having a visual guidance component to pass to a target through a port; defining a path to a location of the target for the robot; and in accordance with a position and orientation of the robot, guiding an ultrasonic probe along the path to permit 2 Appeal2017-011019 Application 14/361,943 engagement of the probe to collect ultrasonic images at positions along the path The claims stand rejected as follows: Claims 1, 9, 14, and 22 have been rejected under 35 U.S.C. § 101 as directed to non-statutory subject matter. Claims 1, 4, 8, 9, 11-14, 17, 21, 22, 24, and 25 have been rejected under 35 U.S.C. § I02(b) as anticipated by DiMaio. 3 Claims 2, 3, 15, 16, and 23 have been rejected under 35 U.S.C. § I03(a) as unpatentable over DiMaio. Claims 5-7 and 18-20 have been rejected under 35 U.S.C. § I03(a) as unpatentable over DiMaio in view of Kuniyasu. 4 NON-STATUTORY SUBJECT MATTER Issue The issue with respect to this rejection is whether the Examiner properly determined that are directed to non-statutory subject matter. The Examiner finds that, while the claims recite either an apparatus or a method, the claims rely on defining a path to place imaging components, introducing imaging components to the inside of the body, and acquisition of images, which is considered an abstract idea, or a concept similar to those found by the courts to be abstract, as it involves certain methods of organizing human activity, an idea of itself ( organizing information through mathematical corre[]lations ) 3 DiMaio et al., US 2009/0036902 Al; published Feb. 5, 2009 ("DiMaio"). 4 Kuniyasu et al., US 2009/0247875 Al; published Oct. 1, 2009 ("Kuniyasu"). 3 Appeal2017-011019 Application 14/361,943 and mathematical relationship/formulas (prong 1 of the two- part test). Ans. 3. The Examiner goes on to find that the structural elements or steps are specified at a high level of generality, to a method already "well known in the art" and are not "enough" to supply the "inventive concept" needed to transform the abstract idea into a patent-eligible invention. Ans. 4. Appellants argue that, with respect to claims 1-13, the claims recite a system with specific structural elements creating physical machine or device. Appeal Br. 8. Appellants contend that the claims are not directed to an abstract idea. Id. Turning to claims 14--25, Appellants argue that the claims are directed to a method employing specific pieces of hardware and that this is more than an abstract idea. Appeal Br. 10. Appellants argue that while claims 14 and 22 may involve abstract ideas, the claims recite additional elements which render the claims patentable. Appeal Br. 10. Appellants also contend that the Examiner has improperly oversimplified the claims and has failed to properly account for all of the limitations of the claims. Appeal Br. 11. Appellant also argue that the method recited in the claims does not preempt the use of the abstract idea in different structures or indifferent techniques. Id. Principles of Law An invention is patent-eligible if it claims a "new and useful process, machine, manufacture, or composition of matter." 35 U.S.C. § 101. However, the Supreme Court has long interpreted 35 U.S.C. § 101 to include implicit exceptions: "[l]aws of nature, natural phenomena, and abstract 4 Appeal2017-011019 Application 14/361,943 ideas" are not patentable. E.g., Alice Corp. v. CLS Bank Int 'l, 573 U.S. 208, 216 (2014). In determining whether a claim falls within an excluded category, we are guided by the Supreme Court's two-step framework, described in Mayo and Alice. Alice, 573 U.S. at 217-18 ( citing Mayo Collaborative Servs. v. Prometheus Labs., Inc., 566 U.S. 66, 75-77 (2012)). In accordance with that framework, we first determine what concept the claim is "directed to." See Alice, 573 U.S. at 219 ("On their face, the claims before us are drawn to the concept of intermediated settlement, i.e., the use of a third party to mitigate settlement risk."); see also Bilski v. Kappas, 561 U.S. 593, 611 (2010) ("Claims 1 and 4 in petitioners' application explain the basic concept of hedging, or protecting against risk."). Concepts determined to be abstract ideas, and thus patent ineligible, include certain methods of organizing human activity, such as fundamental economic practices (Alice, 573 U.S. at 219-20; Bilski, 561 U.S. at 611 ); mathematical formulas (Parker v. Flook, 437 U.S. 584, 594--95 (1978)); and mental processes (Gottschalkv. Benson, 409 U.S. 63, 69 (1972)). Concepts determined to be patent eligible include physical and chemical processes, such as "molding rubber products" (Diamond v. Diehr, 450 U.S. 175, 192 ( 1981) ); "tanning, dyeing, making waterproof cloth, vulcanizing India rubber, smelting ores" (id. at 184 n.7 (quoting Corning v. Burden, 56 U.S. 252, 267---68 (1854))); and manufacturing flour (Benson, 409 U.S. at 69 (citing Cochrane v. Deener, 94 U.S. 780, 785 (1876))). In Diehr, the claim at issue recited a mathematical formula, but the Supreme Court held that "[a] claim drawn to subject matter otherwise statutory does not become nonstatutory simply because it uses a 5 Appeal2017-011019 Application 14/361,943 mathematical formula." Diehr, 450 U.S. at 176 and 191 ("We view respondents' claims as nothing more than a process for molding rubber products and not as an attempt to patent a mathematical formula."). Having said that, the Supreme Court also indicated that a claim "seeking patent protection for that formula in the abstract .... is not accorded the protection of our patent laws, []and this principle cannot be circumvented by attempting to limit the use of the formula to a particular technological environment." Id. ( citing Benson and Flook), 187 ("It is now commonplace that an application of a law of nature or mathematical formula to a known structure or process may well be deserving of patent protection."). If the claim is "directed to" an abstract idea, we tum to the second step of the Alice and Mayo framework, where "we must examine the elements of the claim to determine whether it contains an 'inventive concept' sufficient to 'transform' the claimed abstract idea into a patent- eligible application." Alice, 573 U.S. at 221 ( quotations omitted). "A claim that recites an abstract idea must include 'additional features' to ensure 'that the [claim] is more than a drafting effort designed to monopolize the [abstract idea]."' Id. (quoting Mayo, 566 U.S. at 77). "[M]erely requir[ing] generic computer implementation[] fail[ s] to transform that abstract idea into a patent-eligible invention." Id. The PTO recently published revised guidance on the application of § 101. USPTO's January 7, 2019 Memorandum, 2019 Revised Patent 6 Appeal2017-011019 Application 14/361,943 Subject Matter Eligibility Guidance ("Memorandum"). 5 Under that guidance, we first look to whether the claim recites: ( 1) any judicial exceptions, including certain groupings of abstract ideas (i.e., mathematical concepts, certain methods of organizing human interactions such as a fundamental economic practice, or mental processes); and (2) additional elements that integrate the judicial exception into a practical application (see MPEP § 2106.0S(a}-(c), (e}-(h)). Only if a claim (1) recites a judicial exception and (2) does not integrate that exception into a practical application, do we then look to whether the claim: (3) adds specific limitations beyond the judicial exception that are not "well-understood, routine, conventional" in the field (see MPEP § 2106.0S(d)); or (4) simply appends well-understood, routine, conventional activities previously known to the industry, specified at a high level of generality, to the judicial exception. See Memorandum. Analysis We begin our analysis by looking at the claims to determine if they recite a process, machine, manufacture or a composition of matter. Claims 1-13 recite a system that is a machine or combination of machines. Appeal Br. 27-29 (Claims Appx.). Claims 14--25 recite a method or process. Id. at 5 While the rejection was issued before the Memorandum was released, the methodology set forth in the Memorandum applies to this Appeal. 7 Appeal2017-011019 Application 14/361,943 27-32. We agree with the Examiner that the answer to the first part of the Alice/Mayo analysis is yes; the claims fall within the specific categories of patentable subject matter. Turning to the second step of the analysis, we look to the claims to see if they are directed to one or more of the Judicial Exceptions - a law of nature, a natural phenomenon or an abstract idea. Here we disagree with the Examiner's conclusion that the claims are directed to an abstract idea. Claims 1-13 recite a system comprised of several specific and concrete elements including a robotic system having a robot with a visual component and an ultrasonic probe. Appeal Br. 27. The elements are used in combination to locate the ultrasonic probe in a desired location. Id. We agree with Appellants that the claims are directed to a physical embodiment and not an abstract idea. The Examiner contends that the claims are directed to "surgical ... guidance" which is an abstract concept coupled with a generic robot system. Ans. 9. The Examiner finds that the generic components do not rise to the level of something significantly more than the abstract idea. Ans. 4. We are not persuaded by the Examiner's arguments. While the system in claims 1-13 may employ an abstract idea, we agree with Appellants that the recitation of specific physical elements compels a finding that the claims are not directed to an abstract idea per se but to a physical, practical embodiment of the idea. Appeal Br. 8. The Examiner's analysis represents the precise type of analysis the Supreme Court counsels against in Alice. As the Court explained '' [ a ]t some level, all inventions embody, use, reflect, rest upon, or apply laws of nature, natural phenomena, or abstract ideas." Alice Corp., 573 U.S. at 217. 8 Appeal2017-011019 Application 14/361,943 The Court went on and cautioned ''[to] tread carefully in construing this exclusionary principle lest it swallow all of patent law.'' Id. Here the Examiner has construed the exclusion based on an abstract idea too broadly. A similar analysis applies to method claims 14--25. The Examiner contends that the claims are directed to an abstract idea in that the method recited certain steps that the Examiner contends are mental processes. Ans. 3. In support of the contention, the Examiner argues that the following acts consist of mental steps: Id. a surgeon mentally performs the act of defining the path to the location that they want to image, consciously introduces the imaging components, and guides them to the location would at least obtain and compare intangible data [e.g., position, orientation], compare new and stored information and using rules to identify options [ e.g., path guide], use categories to organize, store and transmit information [ e.g., images], and use algorithm for calculating parameters indicating an abnormal condition [ e.g., deviation from path]. While the method claims recite the step of defining a path, which may involve a mental step, the claims also call for introducing a robot through a port and guiding an ultrasonic probe along a path. See, e.g., Claim 14 above. These steps call for physical action - moving the robot and the probe - on the part of the person performing the process. They do not recite mental steps as suggested by the Examiner. Under step (1) of the guidance, we conclude that the claims are not directed to an abstract idea. Even if we were to conclude that the claims are directed to an abstract idea, under the guidance, we must next ask if the claims recite additional 9 Appeal2017-011019 Application 14/361,943 elements that integrate the judicial exception into a practical application. We conclude that they do. As discussed above, the method claims include steps calling for physically moving the robot arm and the ultrasonic probe along the path developed in the determining step. This is a practical application of the determining step. Under the guidance, the claims are deemed to be patent eligible. Having concluded that the claims are directed to patent eligible subject matter we need not address the issue of whether the recited elements are well-understood, routine, conventional. Conclusion We conclude that the Examiner erred in finding that the claims are directed to non-statutory subject matter. ANTICIPATION Issue The issue with respect to this rejection is whether a preponderance of the evidence supports the Examiner's conclusion that the claims are anticipated by DiMaio. The Examiner finds DiMaio discloses a surgical robot guidance system comprising a robot system having a robot configured to pass through a port. Ans. 5. The Examiner finds that the robot system comprises a visual component employed in guiding the robot along a path to a location, where the location is defined in accordance with the location and position of the robot. Id. The Examiner also finds that the system of DiMaio comprises an 10 Appeal2017-011019 Application 14/361,943 ultrasonic probe which is guided by the robot to the location to permit the probe to collect ultrasonic images at the location. Id. Appellants argue that DiMaio does not use the endoscope to guide the robot along a path to a location. Appeal Br. 16. Appellant also argue that DiMaio does not disclose using the robot to guide the ultrasonic probe to a location which is defined in accordance with a position and orientation of the robot. Id. at 17. Appellants contend that DiMaio calls for the user and not the robotic system to control the movement of the robotic arms. Id. at 18. Appellants also argue that DiMaio does not disclose moving the ultrasonic probe to the same position where the visual system was located. Id. Principles of Law [T]he examiner bears the initial burden, on review of the prior art or on any other ground, of presenting a prima facie case of unpatentability. If that burden is met, the burden of coming forward with evidence or argument shifts to the applicant. After evidence or argument is submitted by the applicant in response, patentability is determined on the totality of the record, by a preponderance of evidence with due consideration to persuasiveness of argument. In re Oetiker, 977 F.2d 1443, 1445 (Fed. Cir. 1992). "Anticipation requires that all of the claim elements and their limitations are shown in a single prior art reference." In re Skvorecz, 580 F.3d 1262, 1266 (Fed. Cir. 2009). "[N]ot unlike a determination of infringement, a determination of anticipation, as well as obviousness, involves two steps. First is construing the claim, []followed by, in the case of anticipation or obviousness, a 11 Appeal2017-011019 Application 14/361,943 comparison of the construed claim to the prior art." Key Pharms. v. Hereon Labs. Corp., 161 F.3d 709, 714, 48 USPQ2d 1911, 1915 (Fed. Cir. 1998). "[D]uring examination proceedings, claims are given their broadest reasonable interpretation consistent with the [S]pecification." In re Hyatt, 211 F.3d 1367, 1372 (Fed. Cir. 2000). Analysis We adopt the Examiner's findings of fact, reasoning on scope and content of the prior art, and conclusions set out in the Final Action and Answer regarding this rejection. We find the Examiner has established that the claims are anticipated by DiMaio. Appellants have not produced evidence showing, or persuasively argued, that the Examiner's determinations on anticipation are incorrect. Only those arguments made by Appellants in the Briefs have been considered in this Decision. Arguments not presented in the Briefs are waived. See 37 C.F.R. § 4I.37(c)(l)(iv) (2015). We address Appellants' arguments below. Appellants argue that the endoscope disclosed in DiMaio is not used to guide the robot arm along a path to a location such as a surgical site. Appeal Br. 16. Appellants point to DiMaio where is says that preferably, the endoscope is inserted through a tool guide such as a cannula. Id.; DiMaio We have considered Appellants' argument and are unpersuaded. We interpret DiMaio as teaching that the endoscope plays a role in guiding the robot. As taught by the instant Specification and recited in claim 1, the robot is configured to pass through a port, or entry point in the patient. Spec. 8 (see claim 1 above). The port disclosed in the Specification is akin to the guide tool recited in DiMaio in that it provides a passage through 12 Appeal2017-011019 Application 14/361,943 which the endoscope and probe pass into the body. Spec. 8; DiMaio ,r 46. As taught by DiMaio, when the endoscope exits the guide tool, it transmits images of the region at the end of the tool to the surgeon. See DiMaio ,r 48. As the Examiner points out, those images are capable of being used by the surgeon to position the endoscope, thereby being employed to guide the robot. Ans. 11. Appellants next argue that DiMaio does not teach guiding the ultrasonic probe to the same location as the robot. Appeal Br. 17. Appellant contend that the term "the location" as used in the claims refers to the precise location defined by the position and orientation of the robot that the robot as initially guided to. Id. Again we are not persuaded by Appellants' arguments. To begin, we note that the claim states "the location being defined in accordance with a position and orientation of the robot." Appeal Br. 27 (Claims Appx.). Thus the claim does not call for the location to be a particular location of the robot. Rather, it is defined by any position and orientation of the robot. Moreover, we do not interpret the term "the location" to mean the actual location of the robot. "The location" is simply any position determined using the position and orientation of the robot. Thus, we agree with the Examiner that the term can refer to any location in the patient ( so long as it is determined using the position and orientation of the robot). See Ans. 12. Under this interpretation, we agree with the Examiner that DiMaio discloses a probe that is guided along a path to a location defined in accordance with a position and orientation of the robot. Id. Appellants contend that in the system of DiMaio, the robot arms are controlled by the user and not the robot subsystem. Appeal Br. 18. 13 Appeal2017-011019 Application 14/361,943 Appellants contend that this is not the same as having the robot configured to guide the ultrasonic probe to a specified location. Id. Appellants' argument is unpersuasive. As drafted the claims call for the robot to guide the ultrasonic probe. Appeal Br. 27 (Claims Appx.). This does not preclude the robot from receiving instructions from an operator or from another source. As the Examiner points out, the claim uses the term "robot" which can include a manned robot. Ans. 13. Claims 9, and 11-13 Claim 9 includes the limitation that the device includes "a passive arm coupled to a visual component and employed in separately guiding the visual component to the location, the location being defined in accordance with a position and orientation of the robot." Appeal Br. 19. Appellants contend that DiMaio does not disclose this limitation. Appeal Br. 20. Appellants argue that the arms of DiMaio comprise active joints are therefore not passive. Id. We are not persuaded by Appellants' argument. We have reviewed the Specification and do not find any evidence that Appellants intended the term "passive arm" to have a meaning other than its plain and ordinary meaning. The plain and ordinary meaning of "passive," as reflected in the definition provided at dictionary.com is "not participating readily or actively; inactive." See, https://www.dictionary.com/browse/passive?s=t (accessed January 23, 2019). Using this definition, we interpret the claims to call for the arm to be inactive. The system of DiMaio meets this limitation. DiMaio teaches that there are times when one or more arms are not being used and are inactive. DiMaio ,r 4 7. Thus while the arms may have active joints, there are times when the arms are passive. 14 Appeal2017-011019 Application 14/361,943 Claims 14, 17, 21, 22, 14, and 15 Appellants have argued these claims separately, but the arguments merely refer to the arguments discussed above. Appeal Br. 20-22. For the reasons stated above, we find the arguments unpersuasive. Conclusion of Law We conclude that a preponderance of the evidence supports the Examiner's conclusion that the subject matter of claims 1, 9, 11-13, 14, 17, 21, 22, 24, and 25 are anticipated by Goldfarb. Claims 4, 8, and 14 have not been argued separately and therefore fall with claim 1. 37 C.F.R. § 4I.37(c)(l)(iv). OBVIOUSNESS Rejection Based on DiMaio Alone The issue with this rejection is whether a preponderance of the evidence supports the Examiner's conclusion that the subject matter of claims 2-3, 10, 15, 16, and 23 would have been obvious over DiMaio. The claims at issue in this rejection add the limitation that "the visual component includes an endoscope and the robot deploys the endoscope first and then deploys the ultrasonic probe such that visual images and ultrasonic images are taken at different times but at the same location." Appeal Br. 27 (Claims Appx.). The Examiner finds that while DiMaio teaches that the visual component and the ultrasonic probe can be deployed simultaneously, DiMaio also teaches that the tools can be exchanged if there are space constraints. Ans. 7. The Examiner concludes 15 Appeal2017-011019 Application 14/361,943 Id. It would be obvious to a person of ordinary skill in the art to deploy the endoscope and ultrasound probes one after another. One would be motivated to do so as the camera is intended to gather general information on the surface about the environment, and the ultrasound probe is used to gather more specific information about the tissue. Appellants argue that DiMaio only teaches simultaneous deployment of the endoscope and the ultrasonic probe. Appeal Br. 24. Appellants contend that there is no teaching or suggestion in DiMaio which would lead one skilled in the art to sequentially deploy the endoscope and ultrasonic probe. Id. We have considered the parties' arguments and find that Appellants have the better position. While DiMaio teaches that various tools can be inserted at different times, the Examiner has not pointed to any teaching in DiMaio which would lead one skilled in the art to first insert the endoscope into the patient and then insert the ultrasonic probe. The portion of DiMaio cited by the Examiner merely teaches that the number of tools deployed at any given time will depend on the nature of the procedure and space constraints. DiMaio ,r 4 7. We find nothing in this passage or the other portions of DiMaio cited by the Examiner that would lead one skilled in the art to first deploy an endoscope followed by an ultrasonic probe. We conclude that a preponderance of the evidence does not support the Examiner's conclusion that the subject matter of claims 2-3, 10, 15, 16, and 23 would have been obvious over DiMaio 16 Appeal2017-011019 Application 14/361,943 Rejection based on DiMaio Combined with Kuniyasu The issue with respect to this rejection is whether a preponderance of the evidence supports the Examiner's conclusion that the subject matter of claims 5-7 and 18-20 would have been obvious over DiMaio combined with Kuniyasu. Claim 5 is representative of the claims at issue in this rejection. Claim 5, which indirectly depends from claim 1, recites the additional limitation that the system includes a camera mounted on the ultrasonic probe such that visual and ultrasonic images are acquired concurrently. Appeal Br. 27-28. In addition to the findings discussed above, the Examiner finds that Kuniyasu teaches a camera mounted on an ultrasonic probe such that visual images and ultrasonic images are acquired simultaneously. Ans. 8. The Examiner concludes it would have been obvious to a person having ordinary skill at the art at the time the invention was made to apply the mounting of Kuniyasu to the system of DeMaio, as to provide a combination of the camera and ultrasound probe. The motivation for doing so is that the "combination of the ultrasonic image inside the biological tissue by the ultrasonic probe and an optical image of the biological tissue by the CCD camera enables accurate diagnosis as to existence of a disease and progress of the disease[.]" Ans. 8 ( citing Kuniyasu ,r 2). Appellants contend that Kuniyasu does not teach the use of a robot to guide the ultrasonic probe. Appeal Br. 25. Additionally Appellants argue that Kuniyasu does not remedy the deficiencies of DiMaio. Id. We adopt the Examiner's findings of fact, reasoning on scope and content of the prior art, and conclusions set out in the Final Action and 17 Appeal2017-011019 Application 14/361,943 Answer regarding this rejection. We find the Examiner has established that the subject matter of the claims would have been obvious to one of ordinary skill in the art at the time the invention was made over DiMaio combined with Kuniyasu. Appellants have not produced evidence showing, or persuasively argued, that the Examiner's determinations on obviousness are incorrect. Only those arguments made by Appellants in the Briefs have been considered in this Decision. Arguments not presented in the Briefs are waived. See 37 C.F.R. § 4I.37(c)(l)(iv) (2015). We address Appellants' arguments below. Appellants argue that Kuniyasu does not teach or suggest the use of a robot to guide the ultrasonic probe. Appeal Br. 25. This argument is unpersuasive. The rejection is based on the combined teachings of DiMaio and Kuniyasu. Ans. 8. While Kuniyasu may be silent about using a robot to guide an ultrasonic probe, as discussed above, DiMaio teaches the use of a robot to guide the probe. "Non-obviousness cannot be established by attacking references individually where the rejection is based upon the teachings of a combination of references. [The reference] must be read, not in isolation, but for what it fairly teaches in combination with the prior art as a whole." In re Merck & Co., 800 F.2d 1091, 1097 (Fed. Cir. 1986). Appellants also argue that Kuniyasu does not cure the deficiencies of DiMaio. Appeal Br. 25. As discussed above, we do not find the teachings of DiMaio to be deficient. Therefore, we find this argument unpersuasive. We conclude that a preponderance of the evidence supports the Examiner's conclusion that the subject matter of claims 5-7 and 18-20 would have been obvious over DiMaio combined with Kuniyasu. 18 Appeal2017-011019 Application 14/361,943 SUMMARY We reverse the rejection of claims 1, 9, 14, and 22 under 35 U.S.C. § 101. We affirm the rejection of claims 1, 4, 8, 9, 11-14, 17, 21, 22, 24, and 25 under 35 U.S.C. § 120(b) as anticipated by DiMaio. We reverse the rejection of claims 2, 3, 15, 16, and 23 under 35 U.S.C. § 103(a) as unpatentable over DiMaio. We affirm the rejection of claims 5-7 and 18-20 under 35 U.S.C. § 103(a) as unpatentable over DiMaio combined with Kuniyasu. No time period for taking any subsequent action in connection with this appeal may be extended under 37 C.F.R. § 1.136(a). AFFIRMED-IN-PART 19 Copy with citationCopy as parenthetical citation