Ex Parte McIntyre et alDownload PDFPatent Trial and Appeal BoardMar 23, 201713875425 (P.T.A.B. Mar. 23, 2017) Copy Citation United States Patent and Trademark Office UNITED STATES DEPARTMENT OF COMMERCE United States Patent and Trademark Office Address: COMMISSIONER FOR PATENTS P.O.Box 1450 Alexandria, Virginia 22313-1450 www.uspto.gov APPLICATION NO. FILING DATE FIRST NAMED INVENTOR ATTORNEY DOCKET NO. CONFIRMATION NO. 225525.44 5633 EXAMINER MACAULEY, SHERIDAN R ART UNIT PAPER NUMBER 1653 MAIL DATE DELIVERY MODE 13/875,425 05/02/2013 Gavin McIntyre 27162 7590 03/23/2017 CARELLA, BYRNE, CECCHI, OLSTEIN, BRODY & AGNELLO 5 BECKER FARM ROAD ROSELAND, NJ 07068 03/23/2017 PAPER Please find below and/or attached an Office communication concerning this application or proceeding. The time period for reply, if any, is set in the attached communication. PTOL-90A (Rev. 04/07) UNITED STATES PATENT AND TRADEMARK OFFICE BEFORE THE PATENT TRIAL AND APPEAL BOARD Ex parte GAVIN MCINTYRE, JACOB WINISKI, SUE VAN HOOK, LUCY GREETHAM, and COURTNEY HART Appeal 2016-0030331 Application 13/875,425 Technology Center 1600 Before ERIC B. GRIMES, RICHARD M. LEBOVITZ, and JOHN G. NEW, Administrative Patent Judges. LEBOVITZ, Administrative Patent Judge. DECISION ON APPEAL This appeal involves claims directed to methods of producing a fimgal leachate solution and methods of using the leachate to grow fungus. The Examiner rejected the claims as anticipated under 35 U.S.C. § 102 and as obvious under 35 U.S.C. § 103(a). We have jurisdiction under 35 U.S.C. §134. The rejections are affirmed. 1 The Appeal Brief (“Appeal Br.”) 2 lists Ecovative Design LLC of Green Island, New York as the real-party-in-interest. Appeal 2016-003033 Application 13/875,425 STATEMENT OF THE CASE The Specification teaches that “utilizing waste streams from various substrates and manufacturing processes to produce liquid media for cultivating fungal biomass has been well explored.” Spec. 1:13—15. The Specification also teaches the “[n]one of these examples utilize a fungus as the primary agent for processing lignocellulose into water soluble components that can be used to produce liquid culture media.” Id. at 1:22— 2:2. The Specification further teaches: “Accordingly, it is an object of the invention to employ leachate as a liquid culture medium for cultivating fungi.” Id. at 2:7—8. The Specification teaches that the leachate can be produced by adding water to a substrate colonized with a selected fungus and where the substrate “is leached in water to obtain a combination of water soluble products” from the substrate which are subsequently used to grow fungi. Id. at 2:21—22. Claims 2—10, 12, 13, and 15 stand finally rejected by the Examiner as follows: 1. Claims 2—5, 7, and 8 under pre-AIA 35 U.S.C. § 102(b) as anticipated by or, in the alternative, under pre-AIA 35 U.S.C. § 103(a) as obvious over Szuecs (US 2,505,811, pat. May 2, 1950). Final Rej. 4. 2. Claims 2—6 and 8 under pre-AIA 35 U.S.C. § 102(b) as anticipated by or, in the alternative, under pre-AIA 35 U.S.C. § 103(a) as obvious over Dale et al. (US Pat. Appl. Publ. 2007/0227063 Al, publ. Oct. 4, 2007) (“Dale”). Final Rej. 5. 3. Claims 2—10, 12, and 13 under pre-AIA 35 U.S.C. § 103(a) as obvious over Dale and Siddhant (Recycling of Spent Oyster Mushroom 2 Appeal 2016-003033 Application 13/875,425 Substrate to Recover Additional Value, 5 Kathmandu University Journal of Science, Engineering and Technology 66—71 (2009)). Final Rej. 8. 4. Claims 2—10, 12, 13, and 15 under pre-AIA 35 U.S.C. § 103(a) as obvious over Dale, Siddhant, and Stamets (US Pat. Appl. Publ. 2004/0211721 Al,publ. Oct. 28, 2004). Final Rej. 11. Claim 2 is representative of the claimed subject matter and is reproduced below: 2. A method of producing a fungal leachate solution comprising the steps of obtaining a feedstock of lignocellulosic substrate; colonizing said substrate with a selected fungi to effect decomposition of said feedstock and to leach out water soluble compounds therefrom including at least one of a sugar alcohol, a phenolic compound and a fatty acid; and adding water to said colonized substrate to form a liquid medium containing said at least one of a sugar alcohol, a phenolic compound and a fatty acid. CFAIM INTERPRETATION Claim 2 requires “colonizing said substrate with a selected fungi to effect decomposition of said feedstock and to leach out water soluble compounds therefrom including at least one of a sugar alcohol, a phenolic compound and a fatty acid.” The term “colonizing” is not defined in the Specification. We give the term “colonizing” its ordinary dictionary meaning that would be understood by one of ordinary skill in the art in light of the Specification to mean “establish itself in (an area).”2 Consistently, the Specification describes inoculating a substrate with a fungus and growing the fungus on 2 https://en.oxforddictionaries.com/defmition/colonize. 3 Appeal 2016-003033 Application 13/875,425 the substrate. Spec. 5:14—17. Thus, “colonizing said substrate with a selected fungi” means that the fungi is added to the substrate and established, e.g., grown, on the substrate. The “selected fungi” is colonized on the feedstock “to effect decomposition of said feedstock and to leach out water soluble compounds therefrom.” The term “decomposition” is given its ordinary meaning to mean “break down or cause to break: down into component elements or simpler constituents.”3 In other words, the fungus metabolizes the feedstock as it colonizes it, resulting in the production of “at least one of a sugar alcohol, a phenolic compound and a fatty acid.” During the colonizing step, the claim further requires “to leach out water soluble compounds therefrom,” i.e., leach out from the feedstock. Leach means to “(with reference to a soluble chemical or mineral) drain away from soil, ash, or similar material by the action of percolating liquid.”4 Thus, as the fungi decomposes the substrate into “at least one of a sugar alcohol, a phenolic compound and a fatty acid,” these water-soluble chemicals drain from the substrate. The claim does not require the chemicals to be removed or separated. Thus, the claim is satisfied when the soluble products drain from the feedstock substrate, e.g., into water present in the feedstock substrate, but remain in contact with the feedstock. The claims require “adding water to said colonized substrate to form a liquid medium containing said at least one of a sugar alcohol, a phenolic compound and a fatty acid.” Since the water is added to the substrate, and 3 https://en.oxforddictionaries.com/defmition/decompose. 4 https://en.oxforddictionaries.com/defmition/leach. 4 Appeal 2016-003033 Application 13/875,425 no separation step is required, the resulting “liquid medium,” which is said to be formed upon the addition of water, can include solid substrate. ANTICIPATION BASED ON SZUECS The Examiner found that Example 1 of Szuecs describes all the steps of the claimed method. Final Rej. 4—5. Appellants contend the Examiner erred because Szuecs does not describe decomposing a feedstock nor producing a leachate. Appeal Br. 6— 7; Reply Br. 3, 4. We address each of these arguments below. Decomposition Claim 2 requires “colonizing said substrate with a selected fungi to effect decomposition of said feedstock.” “Decomposition” is interpreted to mean that the fungi breaks down or metabolizes the substrate into water- soluble chemicals, including “at least one of a sugar alcohol, a phenolic compound and a fatty acid.” See Claim Interpretation supra. Example 1 of Szuecs describes growing the fungus on a substrate comprising peanut meal for about 10 days to cover the substrate with mycelium. Szuecs, col. 1,1. 53—col. 2,1. 2; col. 3,11. 1—6. While decomposition of the substrate is not expressly described by Szuecs, the Examiner found that “the fungi would decompose the feedstock to utilize nutrients from the feedstock.” Final Rej. 4. The Examiner also found The reference also specifically teaches that the mycelium grows densely throughout the substrate (col. 3, lines 1—7). In order to grow throughout the substrate, the mycelium must absorb nutrients from its environment, which it must do by decomposing the organic matter in order to utilize it for energy. In other words, the growth of the mycelium in the substrate 5 Appeal 2016-003033 Application 13/875,425 effects decomposition of the substrate because the fungus breaks down and utilizes the nutrients in the substrate during growth. Thus, since [Szuecs] teaches fungal growth in the substrate, the reference inherently teaches decomposition of the feedstock. Ans. 3. Appellants contend that the Examiner erred and provided no evidence to substantiate this finding that the fungi decomposes the substrate. Reply Br. 3. We do not agree that the Examiner erred. The Examiner’s position is well-reasoned and scientifically sound. We do not believe it is necessary to provide additional factual evidence that a fungus needs nutrients to grow and that such growth involves metabolizing the substrate (“decomposition”) on which it is grown to produce chemical breakdown products. Such finding that an organism digests (metabolizes, decomposes, breaks down) the food (substrate) it eats to extract nutrients is so well-known that it does not require a factual source to establish its veracity. Appellants did not adequately explain a flaw in the Examiner’s reasoning or fact finding. Leach out The claim also requires that water soluble compounds “leach out” from the substrate. We interpreted this to mean that the water soluble compounds drain from the feedstock, but can remain in contact and unseparated from it. See Claim Interpretation supra. The Examiner found that Szuecs produces a fungal leachate solution, such as the “‘essence of mushroom’” described in Example 1 of Szuecs. Ans. 2—3. Appellants contend that the Examiner did not provide evidence that a fungal leachate would necessarily form. Appeal Br. 7—8. Appellants also contend that “the Examiner is in error to posit that the addition of moisture to the substrate of 6 Appeal 2016-003033 Application 13/875,425 Szuecs would inherently result in the leaching of some water soluble compounds from the substrate.” Reply Br. 4—5. Appellants’ argument does persuade us of Examiner error. Szuecs, as found by the Examiner, inoculates a substrate with fungus. Szuecs, col. 2,11. 7—8. The substrate explicitly is described to contain water: “This mixture [peanut meal, peat, sulfuric acid] is heated at 15 lbs. steam pressure for 30 minutes. Then there are mixed therewith: 6000 g. calcium carbonate (CaCCE), 2000 g. ground wheat soaked in 5000 cc. water.'1'’ Id. at col. 2,11. 3—6 (emphasis added). Appellants’ statement that “there is no water in the mycelium-inoculated feedstock” (Appeal Br. 7) is therefore inconsistent with the factual evidence provided by the Examiner. The Examiner’s finding that water-soluble compounds produced by the growing and metabolizing fungi would drain into the water of the feedstock is reasonable. As found by the Examiner, the same fungus described in the Specification — Pleurotus ostreatus (Spec. 8 (Example 1)) — is also described in Szuecs (Szuecs, col. 4,1. 72). Consequently, the Examiner had reasonable basis to believe that Szuecs’s fungus would produce the same water-soluble compounds as claimed, shifting the burden to Appellants to show that it does not. (Once “the PTO shows sound basis for believing that the products of the applicant and the prior art are the same, the applicant has the burden of showing that they are not.” In re Spada, 911 F.2d 705, 708 (Fed. Cir. 1990).) Appellants did not meet this burden. Because the products of the decomposition are water-soluble, they would necessarily drain into the water moisture present in the feedstock. Appellants attempt to rebut this finding by arguing that the substrate in Szuecs is characterized as crumbly or of granular structure. Appeal Br. 5, 6, 7 Appeal 2016-003033 Application 13/875,425 7. However, Szuecs expressly teaches the presence of water in the feedstock substrate (Szuecs, col. 2,1. 6) and characterizes its water content: • “The water content of the material is preferably adjusted to within the range of 50 to 65% by weight.” Id. at col. 4,11. 13—15. • “The resulting substrate contains 62.7 % water by weight.” Id. at col. 4,11.31-33. As discussed in the claim interpretation section, the claim does not require the water soluble compounds to be separated from the feedstock. Thus, their draining into the water present in the feedstock satisfies the claimed requirement of “to leach out water soluble compounds therefrom.” Appellants have not provided adequate evidence to the contrary. Under Appellants’ reasoning, the fungi grown on the substrate do not break the substrate components down, and do not release water-soluble compounds into the water, both contentions which are contrary to scientific principles that organisms metabolize food sources in order to grow and that metabolism produces break-down products that, when water-soluble, would necessarily dissolve in the water comprising the substrate. In sum, the anticipation rejection of claim 2 by Szuecs is affirmed. Claim 8 Claim 8 further requires “wherein said feedstock is soaked in said water for a period sufficient to leach out said water soluble compounds and to form a slurry comprised of liquid leachate and solid substrate.” The Examiner found that water is added to Szuecs’ substrate which would form a slurry of the substrate in water. Final Rej. 4. The Examiner’s finding is supported by a preponderance of the evidence because the fungus is grown 8 Appeal 2016-003033 Application 13/875,425 in the substrate, comprising water, for ten days, which would necessarily form a slurry because of the presence of the water. Szuecs, col. 3,11. 1—7; col. 2,11. 5—6. Appellants contend that this step is not described in Szuecs, but did not identify an error in the Examiner’s findings. Appeal Br. 10. Accordingly, the anticipation rejection of claim 8 by Szuecs in affirmed. Claim 3—5 and 7 Appellants did not provide separate arguments for claims 3—5 and 7. Appeal Br. 10. These claims therefore fall with claim 2. 37 C.F.R. §41.37(c)(l)(iv). ANTICIPATION REJECTION BASED ON DALE The Examiner found that Dale describes all the steps of the claimed method. Final Rej. 5—6. The Examiner found that Dale describes the use of Pleurotus ostreatus, the same fungus employed in the Specification. Id. at 6. Based on the identity between the fungus employed by Dale and in the Specification, the Examiner found that the water-soluble products would leach from the feedstock and into the liquid medium. Id. Appellants contend that there is no disclosure in Dale of a fungal leachate comprising at least one of a sugar alcohol, a phenolic compound and a fatty acid as required by claim 2. Appeal Br. 11. Appellants also contend there is no adding water as required by the claim. Id. As explained below, Appellants’ arguments are not supported by adequate evidence. Dale teaches that Mushroom Spent Straw (MSS) is produced after fungal growth on a lignocellulosic substrate. Dale 1 8. Mushrooms are fungi. The MSS is grown under 85% moisture conditions, and thus 9 Appeal 2016-003033 Application 13/875,425 reasonably would contain water as found by the Examiner. Id. 123. See Final Rej. 6. Leaching of water-soluble compounds into the water present in the MSS would be reasonably expected because the same fungi are used in both Dale and in the Specification, and thus would be reasonably expected to produce the same water-soluble compounds upon decomposition. Because the compounds are water-soluble they necessarily dissolve in water and thus would “leach out” from the MSS into the water present in it as required by claim 2 (“to leach out water soluble compounds therefrom”). Dale teaches that the MSS is “soaked and stirred in distilled (de ionized) water.” Dale 130. This step involves the addition of water and thus meets the claim limitation of “adding water to said colonized substrate to form a liquid medium containing said at least one of a sugar alcohol, a phenolic compound and a fatty acid.” The Examiner also cited paragraph 35 of Dale as containing anticipatory disclosure because it teaches cultivating mushrooms on rice straw, a lignocellulosic feedstock (claim 2: “colonizing said substrate with a selected fungi to effect decomposition of said feedstock”), in a humid environment which would result in some leaching of the water-soluble compounds into the water present in the straw (claim 2: “to leach out water soluble compounds therefrom”), and subsequent extraction of the MSS “with water to remove enzymes/proteins, organic acids, soluble lignin and oligosaccharides” (Ans. 8) (claim 2: “adding water to said colonized substrate to form a liquid medium containing said at least one of a sugar alcohol, a phenolic compound and a fatty acid”). The Examiner finds that lignin is a phenolic compound (Ans. 8). 10 Appeal 2016-003033 Application 13/875,425 With respect to the disclosure cited by the Examiner at paragraph 30, Appellants argue that Dale “relates to a byproduct produced in accordance with [0015] - [0020] after the growth of mushrooms and specifically, treating the waste . . . with an AFEX process using pressurized hot liquid ammonia which is rapidly depressurized to release the ammonia treated solid as the byproduct.” Appeal Br. 11. Appellants do not explain why the Examiner’s findings are deficient. The disclosure at paragraphs 15—20 of Dale describes growing mushrooms under conditions where degradation occurs. Paragraph 17 of Dale expressly refers to separating out the liquid, indicating that water is present and that such water would contain the soluble compounds produced during the mushroom growth. A step of adding water is not recited here. However, the Examiner relied upon Dale’s paragraphs 30 and 35 for such steps. In paragraph 30, as already discussed, the spent MSS is soaked in water after growth. Similar disclosure, as discussed above, is also described in paragraph 35 of Dale. With respect to the Examiner’s findings based on paragraph 35 of Dale, Appellants dispute that leaching out would occur, stating that “since the bags are made of polythene, the Examiner has not explained how water- soluble compounds inside the bags would be extracted through the bags into condensate on the outside of the bags.” Appeal Br. 12. We note that the Examiner referred to “a condensate containing a leachate would form on the polythene bags in which the mushrooms are cultivated.” Ans. 9. However, this statement does not require the condensate to form on the outside of the bag; the condensate could form on the inside, as well. Nonetheless, we do not rely on this finding in reaching 11 Appeal 2016-003033 Application 13/875,425 the determination that Dale teaches that water-soluble compounds “leach out” from the feedstock. Rather, Dale’s teaching of moisture conditions of 85% (Dale 123), the explicit disclosure of the presence of water in the grass substrate on which the fungus is grown {id. 117) provides reasonable basis to believe that the feedstock contains water and that the water-soluble compounds produced during fungal growth would leach into the water because of the normal chemical property of water-soluble compounds to dissolve in water. Appellants also contend there is no decomposition or colonization of the substrate (Reply Br. 6), but provide no evidence to support this position, particular when Dale expressly describes growing the fungus on substrate and decomposing it into various components, including oligosaccharides. Dale 11 8, 15, 30,35. In sum, the anticipation rejection of claim 2 by Dale in affirmed. Claim 8 Claim 8 further requires “wherein said feedstock is soaked in said water for a period sufficient to leach out said water soluble compounds and to form a slurry comprised of liquid leachate and solid substrate.” The Examiner found that water is added to the substrate which would form a slurry of the substrate in water. Final Rej. 6. The Examiner’s finding is supported by a preponderance of the evidence because the spent straw is “soaked” in water which would necessarily form a slurry because of the presence of the water. Dale 130. Appellants contend that this step is not described in Dale, but did not identity an error in the Examiner’s findings. 12 Appeal 2016-003033 Application 13/875,425 Appeal Br. 12. Accordingly, the anticipation rejection of claim 8 by Dale is affirmed. Claims 3—6 Appellants did not provide separate arguments for claims 3—6. Appeal Br. 12. These claims therefore fall with claim 2. 37 C.F.R. §41.37(c)(l)(iv). OBVIOUSNESS IN VIEW OF DALE AND SIDDHANT Claims 12 and 13 further require inoculating the liquid medium, obtained from the first step of colonizing substrate, with a fungus. The Examiner found that Dale does not describe this step, but found that this deficiency is met by Siddhant. The Examiner found: [Siddhant] teaches a method of obtaining a feedstock of lignocellulosic substrate (wheat straw) and colonizing the substrate with a fungus to produce a spent mushroom substrate (p. 66, par. 4-p. 67, par. 1). The reference teaches inoculating a medium comprising a lignocellulosic feedstock and the spent substrate with a selected fungus and incubating the inoculated medium to effect metabolizing and colonization of the medium (p. 67, par. 2). Final Rej. 9—10. The Examiner found that both Dale and Siddhant teach the desirability of recycling of spent mushroom substrate. Final Rej. 10. The Examiner found that one of ordinary skill in the art would have recognized that the liquid produced by Dale could be used as a medium on which to culture mushrooms. Id. Appellants contend that Dale and Siddhant are non-analogous art. Appeal Br. 13. Appellants contend that “Dale is directed to a process for the 13 Appeal 2016-003033 Application 13/875,425 conversion of waste grass into byproducts and not the growing of mushrooms” and therefore “no purpose would be achieved by adding fresh wheat straw to the grass waste of Dale in order to convert the mixture into byproducts.” Id. Appellants also contend: While Dale discloses a use for the solid produced from the growth of mushrooms {see 0016] there is no disclosure of a use for the liquid produced from the growth of mushrooms and which comprises enzymes and degraded lignin. Id. at 15. Discussion Dale teaches adding water to mushroom spent straw on which fungus has been cultivated and separating the MSS into substrate and water. Dale 1130, 35. Dale teaches that the spent substrate is treated to obtain sugars which can be used in ethanol production. Id. H 6, 36. Dale teaches that the liquid water is a source of lignin, oligosaccharides, organic acids and other products. Id. H 28, 35, 37. Siddhant also teaches utilizing spent straw substrate on which mushrooms have been cultivated. Siddhant, Abstract. Siddhant describes taking spent substrate after cultivation, autoclaving it, and then mixing it with fresh wheat straw and growing fungus (mushrooms) on it. Siddhant 67 (See section titled: “As ingredient in the cultivation of other oyster mushroom species”) (emphasis omitted). Appellants contend that Dale and Siddhant are non-analogous prior art. Prior art which is pertinent to the claimed invention is referred to as “analogous” prior art. It is well-established that there are two criteria to be applied when determining whether a reference is analogous prior art: (1) 14 Appeal 2016-003033 Application 13/875,425 whether the reference is from the “same field of endeavor” as the claimed invention, and (2) if the reference is not within the same field of endeavor, “whether the reference still is reasonably pertinent to the particular problem with which the inventor is involved.” In re Clay, 966 F.2d 656, 658—59 (Fed. Cir. 1992). “References are selected as being reasonably pertinent to the problem based on the judgment of a person having ordinary skill in the art.” In re Kahn, 441 F.3d 977, 986—87 (Fed. Cir. 2006). When neither criterion is met from the perspective of a person having ordinary skill in the art, the reference is deemed “non-analogous” and is not considered pertinent to the § 103 determination. In this case, Dale, Siddhant, and the claimed invention relate to the cultivation of fungus, and then recycling for different purposes the spent straw on which the fungus was grown. Appellants consider Dale and Siddhant to be non-analogous because Dale utilizes the spent substrate to make ethanol, while Siddhant uses it to grow more mushrooms on. Yet, as pointed out by the Examiner (and supported by a preponderance of the evidence as discussed supra), both publications recycle the spent straw, making it reasonable for a person of ordinary skill in the art to have consulted Dale as to how to make spent mushroom straw for recycling in Siddhant’s method and to have recognized that Dale’s lignocellulosic waste products (see Dale 135) could be utilized for mushroom cultivation instead of treatment for the purpose of making ethanol. Moreover, Dale teaches that spent straw has a variety of uses, including burning, land fill, compost, animal feed, for making bio-plastics, and to make ethanol. Dale H 6, 8, 9. Consequently, a preponderance of the evidence shows that, at the time of the invention, it was widely known that spent straw had numerous uses. Thus, 15 Appeal 2016-003033 Application 13/875,425 while Dale discloses one specific use of its own spent straw substrate, one of ordinary skill in the art would have known that Dale’s spent straw could be used in any one of the other conventional uses of it, including as a substrate for further fungi cultivation as described in Siddhant. Appellants also argue that Dale uses the solid from the spent straw, not the liquid as recited in claims 12 and 13. Appeal Br. 15, 16. The Examiner responded: One of ordinary skill in the art would therefore recognize that the spent mushroom substrate of Dale, containing at least some liquid medium as remaining moisture, could be inoculated with a selected fungus and incubated to effect metabolizing and colonization of the medium, since [Siddhant] provides motivation for the reuse of the spent mushroom substrate in the method of Dale. It is noted that the claims do not require that the liquid be separated from the spent mushroom substrate. Thus, the colonization of the spent mushroom substrate, which would contain at least some liquid, teaches the limitations of the claims. Appellants’ arguments have therefore not been found to be persuasive. Ans. 13. As explained above in the Claim Interpretation section, the interpretation of “liquid medium” to permit the inclusion of solid substrate is reasonable because the claims do not recite a step of separating the liquid and recite that a “liquid medium” is formed when water is added to the solid “colonized substrate.” Thus, the recited “liquid medium” includes the mushroom spent straw (MSS) prior to extraction and after extraction as described by Dale (e.g., Dale ^fl[ 30, 35). One of ordinary skill in the art, upon reading Siddhant’s teaching that spent straw can be recycled for use as a substrate for additional fungus growth, would have recognized that Dale’s MSS (either before separation 16 Appeal 2016-003033 Application 13/875,425 into substrate straw and liquid, or after separation when some liquid would remain) be useful for such purpose because it constitutes the same type of spent mushroom straw as described by Siddhant. For the foregoing reasons, the obviousness rejection of claims 12 and 13 is affirmed. OBVIOUSNESS IN VIEW OF DALE, SIDDHANT, AND STAMETS Independent claim 15 has similar steps as claim 2, but further recites “obtaining a feedstock of rye straw” and “to leach out water soluble compounds including at least one of a sugar alcohol, a phenolic compound and a fatty acid and chlamydospores therefrom.” Chlamydospores are asexual fungal spores. Spec. 3. The Examiner relied on Dale and Siddhant as discussed above, and further cited Stamets for teaching rye straw. Appellants contend that there is no teaching of chlamydospores. Appeal Br. 17. However, the Specification states that “leachate derived from rye straw (colonized and decomposed as described above). . . demonstrates a specific effectiveness at stimulating germination of asexual spores, namely chlamydospores.” Spec. 3. Thus, substituting rye straw, as suggested by Stamets, in the process made obvious by Dale and Siddhant would reasonably be expected to result in leaching chlamydospores along with water soluble compounds. In any event, claim 15 does not require chlamydospores because it recites “at least one of’ a group which includes chlamydospores, but therefore only requires one member of the group. The rejection is therefore affirmed. 17 Appeal 2016-003033 Application 13/875,425 Summary Rejections 1—4 are affirmed. To the extent claims were not separately argued, they fall with claims 2, 12, 13, and 15. 37 C.F.R. 41.37(c)(l)(iv) TIME PERIOD No time period for taking any subsequent action in connection with this appeal may be extended under 37 C.F.R. § 1.136(a)(l)(iv). AFFIRMED 18 Copy with citationCopy as parenthetical citation