Ex Parte Hanafusa et alDownload PDFPatent Trial and Appeal BoardApr 27, 201612525947 (P.T.A.B. Apr. 27, 2016) Copy Citation UNITED STA TES p A TENT AND TRADEMARK OFFICE APPLICATION NO. FILING DATE 12/525,947 08/05/2009 74384 7590 Cheng Law Group, PLLC 1133 13th St. N.W. Suite C2 Washington, DC 20005 04/27/2016 FIRST NAMED INVENTOR Nobuhiro Hanafusa UNITED STATES DEPARTMENT OF COMMERCE United States Patent and Trademark Office Address: COMMISSIONER FOR PATENTS P.O. Box 1450 Alexandria, Virginia 22313-1450 www .uspto.gov ATTORNEY DOCKET NO. CONFIRMATION NO. NOG-0332 2647 EXAMINER DAUNER, JOSEPH G ART UNIT PAPER NUMBER 1634 MAILDATE DELIVERY MODE 04/27/2016 PAPER Please find below and/or attached an Office communication concerning this application or proceeding. The time period for reply, if any, is set in the attached communication. PTOL-90A (Rev. 04/07) UNITED STATES PATENT AND TRADEMARK OFFICE BEFORE THE PATENT TRIAL AND APPEAL BOARD Ex parte NOBUHIRO HANAFUSA, KORETSUGU OGATA, TAKAHIRO NISHIMOTO and MASKI KANAI 1 Appeal2014-001496 Application 12/525,947 Technology Center 1600 Before FRANCISCO C. PRATS, ULRIKE W. JENKS, and JOHN E. SCHNEIDER, Administrative Patent Judges. SCHNEIDER, Administrative Patent Judge. DECISION ON APPEAL This is an appeal under 35 U.S.C. § 134 involving claims to micro- fluid reactor plates, which have been rejected as obvious. We have jurisdiction under 35 U.S.C. § 6(b ). We reverse. STATEMENT OF THE CASE The invention relates to a reactor plate used for chemical and biological assays and analyses. Spec. i-f 1. The plates contain a series of 1 Appellants identify the Real Party in Interest as Shimadzu Corporation. Appeal Br. 2. Appeal2014-001496 Application 12/525,947 micro chambers comprising wells in the surface of a reactor plate. Spec. ,-r 2. Channels are provided for introducing materials into the individual chambers and for venting air from the chambers as materials are introduced. Id. The vented air is collected in a variable member such as a bellows. Spec. i-f 29. A switching valve controls the flow of materials entering the chambers and the flow of air into the variable member. Spec. i-f 23. Claims 1-7, 9-13, 16-17 and 19 are on appeal. Claim 1 is illustrative and reads as follows: 1. A reactor plate comprising: a reaction well; a reaction well channel connected to the reaction well, the reaction well channel being constituted from a groove formed in the contact surface between two members bonded together or from the groove and a through hole formed in the member, the reaction well channel including a main channel, a metering channel branched off the main channel and having a predetermined capacity, and an injection channel of which one end is directly connected to the metering channel and the other end is connected to the reaction well, the injection channel being formed narrower than the metering channel not so as to allow the passage of a liquid at a liquid introduction pressure applied to introduce the liquid into the main channel and the metering channel and at a purge pressure applied to purge the liquid from the main channel but so as to allow the passage of the liquid at a pressure higher than the liquid introduction pressure and the purge pressure; a reaction well air vent channel directly connected to the reaction well and formed separately from the reaction well channel; a variable member having an internal capacity being passively variable by expanding and contracting, the variable member being provided in the reactor plate; and 2 Appeal2014-001496 Application 12/525,947 a switching valve being configured to connect the main channel and the reaction well air vent channel to the variable member so as to allow moving a gas in the main channel and the reaction well air vent channel to the variable member in a closed system; thereby the main channel and the reaction well air vent channel are kept hermetically sealed, wherein the main channel has an elongated structure defining a flow path extending in the direction of elongation and where the metering channel branches from a side of the flow path. The claims stand rejected as follows: Claims 1, 3, 5-7, 9-11, 16, 17, and 19 are rejected under 35 U.S.C. §103(a) as being unpatentable over Geiser (WO 2005/070546 Al, published Aug. 4, 2005) ("Geiser") in view of Jedrzejewski (US 2001/0036669 Al, published Nov. 1, 200l)("Jedrzejewski"), Woudenberg (US 6,124,138 Bl, issued Sept. 26, 2000)("Woudenberg") and McNeely (US 2002/0033193 Al, published Mar. 21, 2002)("McNeely"). Claim 2 is rejected under 35 U.S.C. §103(a) as being unpatentable over Geiser in view of Jedrzejewski, Woudenberg and McNeely as applied to claim 1, and in further view of Kellogg '125 (US 2004/0191125 Al, published Sept. 30, 2004)("Kellogg l ")as defined by Kellogg '248 (US 6,143,248 B2, issued Nov. 7, 2000)("Kellogg 2"). Claim 4 is rejected under 35 U.S.C. §103(a) as being unpatentable over Geiser in view of Jedrzejewski, Woudenberg and McNeely as applied to claim 1, and in further view of Kaneko (US 2006/0023030 Al, published Feb. 2, 2006)("Kaneko"). 3 Appeal2014-001496 Application 12/525,947 Claims 12 and 13 are rejected under 35 U.S.C. § 103(a) as being unpatentable over Geiser in view of Jedrzejewski, Woudenberg and McNeely as applied to claim 1, and in further view of Striepeke (US 2005/0238536 Al, published Oct. 27, 2005)(Striepeke"). DISCUSSION Issue All of the claims at issue depend from claim 1. The Examiner has rejected claim 1 under 35 U.S.C. § 103(a) as unpatentable over Geiser in view of Jedrzejewski, Woudenberg and McNeely. Final Act. 6. The Examiner finds that the combination of references teaches a reactor plate having all of the elements of the reactor plate described in claim 1. Id. In particular, the Examiner finds that McNeely teaches the use of a variable member to capture air forced out of a reaction chamber and Woudenberg teaches the use of a switching valve in a reactor plate to control the flow of fluids. Final Act. 11-12. Appellants contend that Woudenberg does not disclose a variable member thus it does not teach the use of a switching valve in combination with a variable member. Appeal Br. 12. In addition, Appellants argue that McNeely does not disclose a variable member that can both expand and contract. Appeal Br. 10-11. The issue with respect to this rejection is whether the Examiner has established by a preponderance of the evidence that claim 1 is obvious over Geiser in view of Jedrzejewski, Woudenberg and McNeely as defined by 35 U.S.C. § 103(a). 4 Appeal2014-001496 Application 12/525,947 Findings of Fact FFl. McNeely discloses a reaction plate with a plurality of reaction wells or chambers. McNeely i-f 44. FF2. McNeely discloses the use of an expandable air bladder to capture air forced out of reaction chambers. McNeely i-f 51. FF2. The air bladders in McNeely have fixed or known volumes. Id. Principles of Law "In rejecting claims under 35 U.S.C. § 103, the examiner bears the initial burden of presenting a prima facie case of obviousness. Only if that burden is met, does the burden of coming forward with evidence or argument shift to the applicant." In re Rijckaert, 9 F.3d 1531, 1532 (Fed. Cir. 1993). "The Patent and Trademark Office (PTO) must consider all claim limitations when determining patentability of an invention over the prior art." In re Lowry, 32 F.3d 1579, 1582, 32 USPQ2d 1031, 1034 (Fed. Cir. 1994). When establishing that claimed subject matter would have been obvious under§ 103, the Examiner may rely on the doctrine ofinherency to show that a reference necessarily describes a claimed feature. Jn re Kao, 639 F.3d 1057, 1070 (Fed. Cir. 2011 ). [T]he very essence of inherency is that one of ordinary skill in the art would recognize that a reference unavoidably teaches the property in question." Agilent Technologies, Inc. v. Afjj;metrix, Inc., 567 F.3d 1366, 1383 (Fed. Cir. 2009) (emphasis added); see also In re Oelrich, 666 F.2d 578, 581 (CCPA 1981) ("Inherency, however, may not be established by 5 Appeal2014-001496 Application 12/525,947 probabilities or possibilities. The mere fact that a certain thing may result from a given set of circumstances is not sufficient."). Thus, if "the disclosure is sufficient to show that the natural result flowing from the operation as taught would result in the performance of the questioned function, it seems to be well settled that the disclosure should be regarded as sufficient." Oelrich, 666 F. 2d at 581 (quoting Hansgirg v. Kemmer, 102 F.2d 212, 214 (CCPA 1939)). Analysis Appellants have argued that the Examiner has failed to demonstrate that all of the elements of claim 1 are present in the cited references. Appeal Br. 9. Specifically Appellants have urged that the references fail to teach a "variable member having an internal capacity being passively variable by expanding and contracting." Id. Appellants further argue that while McNeely teaches the use of an "expandable air bladder," McNeely is silent as to whether such bladders can also contract. Appeal Br. 11. The Examiner argues that McNeely discloses an air bladder that performs the same function as the variable member of the instant claims and as such inherently meets the claim limitation. Ans. 5. The Examiner goes on to argue that because the expandable air bladder expands to fill a specific volume, one skilled in the art would recognize that the bladder must be made of a flexible material. Ans. 6. The Examiner then states that a flexible 6 Appeal2014-001496 Application 12/525,947 bladder would inherently have the ability to expand and contract and therefore would have a variable capacity. Ans. 6-7. We find the Examiner's arguments unpersuasive. The Examiner has failed to demonstrate why the air bladders of McNeely inherently must be flexible or able to contract as claim 1 requires. As the Examiner contends, McNeely describes its bladders as being expandable. FF2. Nonetheless, McNeely also teaches that the air bladders have a fixed or known volume. FF3. This supports a finding that the air bladders of McNeely do not necessarily have a variable volume and are not necessarily flexible. Absent a clear showing that the air bladders are made of a flexible material that necessarily is capable of contracting as required by claim 1, a generally finding of inherency cannot be sustained. By itself, the mere likelihood that McNeely's bladder is capable of contracting is insufficient to establish that that property is inherent in the bladder. In re Oelrich, 666 F .2d at 5 81 (cannot establish inherency by probability). We conclude that the Examiner has failed to establish a prima facie case of obviousness and reverse the rejection of claim 1. The remaining claims on appeal depend from claim 1 and include the limitation calling for a variable member. Therefore we reverse the rejection of the remaining claims as well. Conclusion of Law We find that the Examiner has failed to establish by a preponderance of the evidence that claim 1 is obvious over Geiser in view of Jedrzejewski, Woudenberg and McNeely as defined by 35 U.S.C. § 103(a). Because they depend from claim 1 and contain the same limitation regarding a variable member, we also hold that the Examiner has failed to establish that the 7 Appeal2014-001496 Application 12/525,947 remaining claims are unpatentable as obvious as defined by 35 U.S.C. § 103(a). SUMMARY We reverse the rejection of claims 1-7, 9-13, 16-1 7, and 19. REVERSED 8 Copy with citationCopy as parenthetical citation